Patient Exhalation Simulator PES For the evaluation of inhaler misuse conditions and device robustness Exhalation into the mouthpiece of an inhaler prior to the inhalation step is a commonly reported error in patient technique, particularly for dry powder inhaler (DPIs). The consequence of this poor technique may be insufficient drug delivery for effective administration and ultimately, inadequately controlled respiratory disease and/or an overreliance on emergency medication. The Patient Exhalation Simulator (PES) accurately replicates the effects of a patient exhaling into the device mouthpiece prior to the inhalation step. The warm, humid air generated by the PES can be set at flow rates representative of different human exhalation profiles. The PES enables developers to assess how device misuse impacts the critical quality attributes of the inhaler, empowering device design optimisation to ensure robust drug delivery. Investigating the impact of exhalation through a device complements current EMA/ISO guidance on understanding device robustness and evaluating performance under conditions simulating patient use. Simple to set-up and easy-to-use Adjustable air flow temperature and flow rate Ideal for assessing a range of patient profiles Works with existing Copley mouthpiece adapters Qualification tools are available

available for air flow temperature and relative humidity verification Air flow temperature and flow rate are adjustable via a digital display Device under test Temperature set-points Qualification & Maintenance• Comprehensive IQ/OQ documentation package available• Extended warranty availablePatient Exhalation Simulator PES Cat. No. Description 9120 Patient Exhalation Simulator - Model PES 9126 Qualification Tools for Patient Exhalation Simulator 9130 IQ/OQ Documentation for Patient Exhalation Simulator PES 1076 PES Extended Warranty - 1 year 1077 PES Extended Warranty - 2 years Copley Scientific...