Emboli Protection Device General Information - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 61 ANGIoGUARD® RX Emboli Capture Guidewire System - - - - - - - - - - - - - - - - - - - 63 Contents Emboli Protection Device

Emboli Protection Device General Information ANGIOGUARD® RX COmPONENtS 1/ Pouch 1 2/ Each component is used for the following: Angioguard® RX Emboli Capture Guidewire with filter basket: • To facilitate placement of diagnostic and interventional devices. • To capture emboli. • 8F (.088” minimum ID) guiding catheter • 6F interventional sheath • Compatible with 0.014” interventional devices. Angioguard® RX Peel away deployment sheath Torque/Locking device Filter basket introducer Peel away introducer Black/Yellow deployment sheath: • To advance the Angioguard® RX Emboli Capture Guidewire with filter...

Emboli Protection Device

Emboli Protection Device ANGIOGUARD® RX Capture effectiveness Angioguard® RX with its Rapid Exchange System is easy to use, providing optimal protection while maintaining blood flow. • Medium & Extra Support Wires - 0.014” compatible wire available in Medium & Extra support for lesion specific access and support of interventional devices • Effective capture of clinically relevant emboli with 100µ pore sizes filter • Excellent crossability - Easy to cross tortuous anatomies with a crossing profile from as low as 3.2F • Rapid Exchange System - Simplified deployment with peel away deployment sheath...

Emboli Protection Device General Information ANGIOGUARD® RX The Angioguard® RX with its Rapid Exchange System is easy to use, providing optimal protection while maintaining blood flow D Distal tip Coil nosecone Distal marker band E Polyurethane membrane (100 micron pores) Nitinol struts Radiopaque marker G Proximal marker band Guidewire (180 cm wire length) How to use the Angioguard® RX emboli capture guidewire system during intervention Retrieval 1. Flush the deployment sheath using a 10 ml syringe with heparinized saline. Flush is complete when saline is visible at the green hub A . 2. Tightenand...

Emboli Protection Device ANGIoGUARD® RX Emboli Capture Guidewire System ORDERING INFORMATION • Guidewire length 180 cm • 0.14” Wire • Guiding Catheter Compatibility: 8F • Sheath Compatibility: 6F CORONARY (medium support) FILTER BASKET SIZE (mm) 4 5 6 VESSEL DIAMETER (mm) 3.0 < vessel ≤ 3.5 3.5 < vessel ≤ 4.5 4.5 < vessel ≤ 5.5 FILTER BASKET SIZE (mm) 5 6 7 8 VESSEL DIAMETER (mm) 3.5 < vessel ≤ 4.5 4.5 < vessel ≤ 5.5 5.5 < vessel ≤ 6.5 6.5 < vessel ≤ 7.5 PERIPHERAL / CAROTID (extra support)