Synthe-Bone
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Reasorbable Bone Regenerator The Future of Dental Implants

What is Synthe-Bone? Synthe-Bone is a range of bone replacement products made of Tricalcium (3-Phosphate in compliance with international standard ASTM F1088-04. The KeraOs product range complies with the maximum requirements of any biomaterial for odontological use. Synthe-Bone’s structure is similar to that of spongy bone trabecules in its interconnected porosity, which allows it to work as osteoconductor support where blood capillaries and osteogenic cells adhere t form bone. Its bioactivity and composition allows them to intervene in the bone remodeling process with full...

The Future of Dental Implants Biofunctionality. Osteoconduction. It delivers excellent mechanic stability, avoiding micro-movement. It preserves the shape and volume of the defect to avoid bone reabsorption. It favours rapid colonisation of proteins and cells. It acts as the ideal support, as it is recognised by the body and blood capillaries and cells adhere to it to form the bone. Excellent Macroporosity and High Microporosity Bioactivity Osteointegration Its excellent microporosity allows for Its microporosity favours cell adhesion and permeability of the cells towards the adhesion of...

Beta-Tricalcium Phosphate Purity > 99% Bioabsorption Bioremodelling • Synthe-Bone superficially reacts with its physiological medium, dissolving and precipitating hydroxyapatite on the surface. • This precipitation leads to the appearance of osteoblasts and collagen fibre that will form immature bone. • Immature bone becomes structured and mature, continuing with the absorption of Synthe-Bone until it is totally replaced by the newly formed bone. Predictable and stable regenerative results “Effective Bone Regeneration” (a) Goldner staining (b) (c) Wheatley staining

Synthe-Bone interactions and bioactivity Micrographs taken at 45 days after implant of Tricalcium Beta-Phosphate with electron microscopy. Initial colonization can be observed with cell nodes (I) that migrate through the implant leading to the formation of fibrin (non mineralized osteoid tissue) (2). There are also some areas where osteoid tissue is mineralized to a larger extent (3) and areas where there is already newly formed bone (4). Micrograph A shows areas of coexistence between non mineral-ized reabsorbed material (fibrin) and structured material (newly formed bone), which implies...

The Future of Dental Implants