What Does It Measure? The Tewameter® TM Hex (successor of the world-wide acknowledged Tewameter® TM 300) assesses the Transepidermal Water Loss (TEWL), indispensable parameter for the evaluation of the water barrier function of the skin, with utmost accuracy and reproducibility. The Measuring Principle Water is constantly evaporating from the skin which is part of the important body’s metabolism. The amount of water (TEWL) is expressed in g/h/m². 30 sensors inside the hollow cylinder of the probe detect the relative humidity and temperature like a camera. The high amount of data allows the user not only to measure inside the probe with high accuracy, but can show results also for the areas right outside the probe, namely skin surface and ambience above the probe.Thus, new, exciting parameters (local skin energy balance and others) may give interesting insights in several research fields. Fields of Application • Indispensable in formulation, efficacy testing and claim support for cosmetics and pharmaceuticals, regarding improvement of the skin barrier function. • Safety tests for products as even slight deficiencies in the skin barrier can be detected. • Dermatological basic research. • Sweat studies (anti-perspirant efficacy testing). • Patch Tests • Educative measurement in occupational health to alert people for the necessity of using skin protection products. • Veterinary medicine and zoology. • Also for the textile, food, packaging and paper/ tissue industry, the measurement is of interest. • Local skin energy balance is an exciting new parameter for different research fields: e.g. sports, nutrition & food supplements, textile, micro circulation, sleep medicine, special cooling products. Advantages of Open Chamber Measurement • Measurement of the TEWL without any influences of the micro climate of the skin (pressure, occlusion, temperature). • No waiting time between the measurements. • With the “open chamber” method of the Tewameter® TM Hex even high water loss values can be detected accurately as no water is collected inside the probe. • Traceable, elaborate calibration of humidity, temperature and TEWL to g/h/m2. • Worldwide most used TEWL measurement method (even approved in space!*). • Several hundreds of performed studies with the Tewameter® prove this fact. Courage+Khazaka electronic GmbH since 1986 Mathias-Brüggen-Str. 91 . 50829 Köln . GERMANY * Study by DermaTronnier, instruments verified for space by Kayser-Threde GmbH on behalf of the DLR space travel management.

Extremely accurate, quick and robust measurement of the TEWL with the information of 30 sensor pairs. A very stable measurement is achieved quickly within 20 seconds. Continuous measurements over longer periods are also possible depending on the application. Due to the high amount of measurement data, the probe can detect the values like a camera. Unobstructed view to the measurement surface and unobstructed evaporation flow. Robust sensor placement in the wall inside the measurement head. Due to the high amount of collected data measurements not only inside the probe but also on top and below...