1. Catalogs
  2. Covaris Inc
  3. M-Series Brochure

M-Series Brochure

M-Series Brochure

M-Series Brochure

Product catalog summary
Overview: The M-Series Focused-ultrasonicators by Covaris are advanced benchtop sample preparation systems utilizing Adaptive Focused Acoustics® (AFA®) technology. These systems are designed for precise DNA/RNA extraction and mechanical shearing, crucial for next-generation sequencing (NGS) and other molecular biology applications.
Key Applications:
  • DNA/RNA Extraction: Efficient extraction from FFPE tissue samples, blood plasma, and dried blood spots, ensuring NGS-grade quality.
  • Mechanical Shearing: Facilitates precision diagnostics with clinical-grade nucleic acid preparation.
  • Chromatin Shearing: Enhances reproducibility and sensitivity for ChIP-Seq.
  • Biomarker Extraction: Extracts nucleic acids and peptides without harsh chemicals, suitable for research and clinical microbiology.
Technology and Features:
  • AFA-energetics® Technology: Combines high-performance electronics, medical-grade transducers, and custom-engineered cuvettes to deliver controlled acoustic energy for sample processing.
  • Real-time Monitoring: Integrated with SonoLab™ software for quality control and precise results.
  • Temperature Control: Allows isothermal processing, minimizing heat-induced bias.
  • Compact Design: Fits on any benchtop, with non-contact, closed vessel processing to prevent contamination.
Models and Specifications:
  • M220: Single-sample processing with a compact design, integrated chiller, and optimized DNA shearing protocols.
  • ME220: Batch processing for 1 to 8 samples, featuring automated water management and user-friendly software.
Technical Specifications:
  • Power Requirements: 100 to 240 VAC, 500 VA, 50 to 60 Hz.
  • Operating Environment: 15 to 32°C.
  • Regulatory Compliance: CE, ETL Mark, and complies with safety and EMC standards.
Conclusion: The M-Series Focused-ultrasonicators provide a reliable and efficient solution for sample preparation in molecular biology, offering standardized results and high reproducibility, making them a preferred choice in genome centers worldwide.
See more

Catalog excerpts

M-Series Brochure-1

M-Series Focused-ultrasonicators

 Open the catalog to page 1
M-Series Brochure-2

M-Series Focused-ultrasonicators Fully-integrated benchtop sample preparation systems powered by Adaptive Focused Acoustics® (AFA®) technology AFA is highly tunable and controllable and thus standardizes pre-diagnostic sample preparation by improving processing robustness and by reducing sample to sample variation. Sample Prep and Sample Processing Examples • DNA/RNA extraction from Formalin-Fixed • DNA extraction from dried blood spots (DBS) Paraffin-Embedded (FFPE) tissue samples - NGS-grade DNA and RNA from FFPE tissue • Extraction of complex and representative cell-free DNA - Improve reproducibility,...

 Open the catalog to page 2
M-Series Brochure-3

M220 Focused-ultrasonicator ...single sample processing at the benchtop • The “Scientist’s Standard” in a compact, easy-to-use system • Precise and accurate results with AFA-energetics • Proven gold standard used in genome centers worldwide • Less than one minute start-up time • Integrated chiller • Optimized pre-loaded mechanical DNA shearing protocols AFA technology in the M220 eliminates operator-induced variations, improves recoveries, increases efficiency, and provides standardized results. Single Box Design Thermo Electric Module Focused-ultrasonicator Assembly Power Board Acoustic Assembly...

 Open the catalog to page 3
M-Series Brochure-4

ME220 Focused-ultrasonicator 1 to 8 sample processing at the benchtop • The “Scientist’s Standard” in a compact, easy-to-use system, formatted for batch-processing • Precise and accurate results with AFA-energetics • Integrated chiller and automated water management • User friendly SonoLab software with preloaded protocols • Less than 2 minute start-up time No refill and maintenance necessary for up to 30 days. The ME220 Focused-ultrasonicator is the multi-sample, multi-application benchtop sample preparation solution for every lab. Focused-ultrasonicator Assembly Automated Water Management AFA...

 Open the catalog to page 4
M-Series Brochure-6

microTUBE • 15 to 500 (1 sample volume range • DNA shearing <1.5 kb fragments • Up to 3x106 cells chromatin shearing • truXTRAC® FFPE and DBS • truCOLLECT® 8 microTUBE Strip • 15 to 130 (1 sample volume range • DNA shearing <1.5 kb fragments • Up to 3x106 cells chromatin shearing • truXTRAC FFPE and DBS miniTUBE • 200 (1 sample volume • DNA shearing to 2, 3, or 5 kb milliTUBE • 1 to 2 mL volume • Up to 3x107 cells chromatin shearing • cfDNA extraction • Tissue biomarker extraction t-PREP • Up to 10 mg tissue samples • Tissue biomarker extraction Information subject to change without notice. For...

 Open the catalog to page 6

All Covaris Inc catalogs and technical brochures

  1. LE220Rsc

    2  Pages

  2. E-Series

    2  Pages

  3. S-Series

    2  Pages

  4. E220evolution

    2  Pages

*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.