SYSTEM Ingenious sample handling PAL RSI and PAL RTC Sample Prep and Injection

PAL System’s new generation of sample preparation and handling instruments.

The PAL System is one of the most widely used and successful sample preparation and handling platforms. 4

The PAL System is one of the most widely used and successful sample preparation and handling platforms. PAL System is your tool box for sample preparation, from a simple liquid injection to complete workflows. A PAL System can be adapted or extended to meet almost any requirement. Numerous options allow to increase sample capacity or add further modules for sample preparation. Listed below are the method steps that a PAL System can perform: – – – – – – – – – – Liquid injection GC and LC – Gas injection – Liquid addition – Headspace sampling – Dynamic headspace sampling – SPME and SPME Arrow sampling...

Sample preparation is the key to success to achieve precise and accurate results. For a typical chromatographical analysis 61 % of time is spent on sample prep, 30 % of errors are linked to sample prep*. Time Spent on Typical Chromatographic Analysis Sources of Error Generated During Chromatographic Analysis Columns Contamination Data Management Sample Preparation Collection Analysis Sample Introduction Chromatography Integration Instrument Calibration * data taken from the book “SAMPLE PREPARATION FUNDAMENTALS FOR CHROMATOGRAPHY” from Agilent Techologies.

PAL RTC - Highest Productivity & Flexibility The PAL RTC with Robotic Tool Change is the logical (r)evolution of the successful PAL-xt product line. It is a robotic platform for the efficient and safe automation of most sample preparation steps. The robotic change of tools enables unattended 24/7 operation, even for multistep workflows and thereby greatly increases the productivity of labs. At the same time process safety is optimized since all operations become traceable. PAL RSI - The Workhorse The RSI is the robust workhorse for analytical labs. It is the cost effective solution for labs in...

Robotic Tool Change (PAL RTC only) The unique Park Station enables the Robotic Tool Change, for productivity - With different syringes available always the ideal one can be selected, for instance one syringe is reserved for standard addition to minimize carryover while 2 others are used for dilution steps. - The RTC speeds up SPME method development by allowing automatic sampling of different types of SPME fibers. - The PAL RTC identifies type of tool and its position automatically. - 162 x 2mL or 60 x lOmL or 20mL vials/tray holder, other vial types and microtiter plates can be handled. -...

! Injector correct position wrong position detected Process safety Missing vial detected Position detection means process safety. Missing vials or the correct position of the injector are detected and traced. Position detection for the temperature controlled stack ensures that the drawer is in the correct position (open / closed) and the temperature is monitored. Minimized carryover and reproducible injection of minute sample volumes Bottom sensing makes sure that small volumes can be injected out of a few µL of sample (e.g. 3 x 1µL out of 5µL). With Constant Force Technology the PAL detects...

The PAL RTC is all about increasing productivity. Robotic Tool Change takes productivity to a new level. PAL RTC with extended x-axis for LC/MS Automation improves process safety Automation is the way to increase productivity and (process) safety in the laboratory. Transferring repetitive or dangerous manual tasks to a robot improves safety. The possibility to run the instrument 24h/day increases throughput, especially for long sample preparations. The PAL RTC was developed to maximize productivity in analytical and clinical labs. Robotic Tool Change (RTC) brings sample preparation to a higher...

Park Station for Robotic Tool Change PAL RTC with standard x-axis for GC & GC/MS Ingeniously productive. – – – Automatic selection of the syringe with optimal accuracy for adding standards or preparing serial dilutions On the fly switching between a syringe tool for the addition of an internal standard and the LC/MS Tool for subsequent analysis Possibility to permanently configure several workflows on one system for a walk-up prep station, e.g. Liquid/ Liquid Extraction and Solid Phase Extraction (SPE) Automated optimization of methods e.g. by selecting the most suitable Solid Phase Micro Extraction...

The PAL RSI is the reliable workhorse for analytical labs. The PAL RSI defines the industry standard for intelligent sample preparation. PAL RSI with extended x-axis for LC/MS Ingeniously reliable. Laboratories work under time pressure and often with a tremendous workload. The reliability of hardware and software should not be something the user has to worry about. Reliability is just expected from every tool. That is exactly what the PAL RSI was designed for. It is a tool that you can rely on. 50.000 PAL systems worldwide are proof of this.

PAL RSI with standard x-axis for GC & GC/MS The most flexible system on the market. RSI is a flexible tool. Its open and modular architecture makes it the most versatile system on the market. Tools can be exchanged readily within minutes. PAL customers working with GC love the possibility to use liquid, headspace or SPME sampling on the same system. LC customers use the PAL because of its huge sample capacity, the range of syringes and valves available.

Transport vial 1 to balance Place vial 1 back Get weighed vial 1 Add sample 2 to vial 2 Workflow 1 (Head 1) Workflow 2 (Head 2) Injection using Head 2 Transport vial 2 to balance

PAL DHR DUAL HEAD Productivity x2 – Two heads can move independently – The heads can execute two independent workflows Headspace sampling with standard addition Parallel injections into two GC- or LC-systems – The software optimizes the time table to maximize productivity – Collision control → process safety and easy programming – 120 or 160 cm wide working area – Combinations of RTC/RSI heads – With an RTC head toolchange expands the options further Application Examples – Automated weighing of samples, combined with the analysis of a weighed sample – High troughput LCMS injections with 2 completely...