ChromoQuant® QF PCR kitAZFFor detection of micro deletions in the Y chromosome;AZFa, AZFb and AZFcThe ChromoQuant® AZF PCR kit is used for fast and accurate routine diagnosis of micro deletions in the Ychromosome Key advantages • Developed in accordance with EAA/EMQN guidelines 2013 • Basic and Extension set of non-polymorfic markers • Heterochromatin marker for analysis of terminal deletion in primary test • Distal and proximal break point analysis AZFa and AZFb are included in the product • GeneMapper and GeneMarker panel templates are available High specificity One core set with markers for AZFa, b and c Two extension sets with markers for determination of the extent of the deletion in AZFa and b respectively. GeneMarker and GeneMapper templates for easy interpretation and reporting are available as downloads Analysis in accordance with guidelines ChromoQuant AZF kit has been developed in order to follow the guidelines for molecular diagnosis given by EAA/EMQN 2013. This means that there are sufficient number of primers to perform the routine analysis of micro deletions in the AZFa, b and c region. Core set and extension set of markers The core set of markers will detect almost all clinically relevant deletions and over 95% of the deletions reported in the literature in the three AZF regions and is sufficient for routine diagnostics. Extension sets included.

Product specification Intended Use Diagnosis of micro deletions in the Y chromosome AZFa, AZFb and AZFc 32 tests for AZFa, b, c – basic set 10 tests for extended diagnosis of AZFa and AZFb 7 non polymorphic markers + 2 controls will detect more than 95% of all deletions reported in the literature. Sufficient for routine diagnosis. sY160 included. AZFa extension set: 4 non polymorphic markers + 2 controls AZFb extension set: 4 non polymorphic markers + 2 controls The core set of markers for AZFa, b and c is analysed in one PCR tube and one capillary. This set of markers gives a diagnosis for deletions...