Guava® Instrument Cleaning Fluid (ICF) Package Insert Technical Support Telephone: 512-381-4397 North America Toll Free: 1-877-785-2323 International Toll Free: + 800-2939-4959 Email: [email protected] www.luminexcorp.com For Research Use Only. Not for use in diagnostic procedures. 4600-0150, Rev M Catalog No. 4200-0140 01/2021 Luminex Corporation 12212 Technology Blvd. Austin, TX 78727 U.S.A.

Guava® Instrument Cleaning Fluid (ICF) Package Insert For Research Use Only. Not for use in diagnostic procedures.

Guava® Instrument Cleaning Fluid (ICF) Package Insert Symbols Glossary You will encounter these symbols throughout this manual. They represent warnings, conditions, identifications, instructions, and regulatory agencies. Biological risks Serial Number Contains sufficient for tests Catalog number Batch code Storage temperature range For Research Use Only. Not for use in Diagnostic Procedures Luminex Technical Support Contact Luminex Technical Support by telephone in the U.S. and Canada by calling: 1-877-785-2323 Contact outside the U.S. and Canada by calling: +1 512-381-4397 International: + 800-2939-4959...

Guava® Instrument Cleaning Fluid (ICF) Package Insert Description The Guava® easyCyte™ and Guava Muse® Systems operate with minimal maintenance and servicing, but the flowcell and fluid system require regular cleaning to ensure proper performance. Guava Instrument Cleaning Fluid (ICF) cleans the fluid system of the Guava easyCyte or Guava Muse System by effectively removing sample clogs and buildup from cell debris, proteins, and reagent dye residues. Although Guava ICF is supplied ready to use with no dilution required, you can mix Guava ICF with bleach as described in this package insert for...

Guava® Instrument Cleaning Fluid (ICF) Package Insert Causes skin and serious eye irritation. If on skin, wash with plenty of soap and water. If in eyes, rinse continuously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Get medical advice/attention. 7. Wear appropriate personal protective equipment (PPE), including a lab coat and disposable gloves, when performing procedures. When using Guava ICF to clean your Guava PCA, Guava easyCyte™ System, or Muse® Cell Analyzer, hhandle all materials as if capable of transmitting infection. Dispose all...

Guava® Instrument Cleaning Fluid (ICF) Package Insert fail to reach the expected number of events after running Quick Clean. In addition, you can clean the system to clear stubborn clogs. Do not leave bleach or any other cleaning agent on the instrument overnight or for an extended period of time. Prolonged exposure to strong cleaning agents will damage the flowcell. Always flush the instrument extensively with water after using any cleaning reagent. At the end of a cleaning cycle always leave the capillary tip submerged in a 1.5 mL tube of fresh deionized water. NOTE: If acquiring whole blood...

Guava® Instrument Cleaning Fluid (ICF) Package Insert Clean the Guava® Muse® System NOTE: Always check the fluid levels in the cleaning and waste bottles whenever you run the Complete Clean procedure. Ensure the cleaning solution bottle is filled with Instrument Cleaning Fluid (ICF). 1. Select Muse System Cleaning under the Essential Tools at the main menu. Select Complete System Clean. Select Run Complete Clean. 4. Follow the prompts to load ICF, followed by deionized (DI) water. Select Finish if you are done, or Next Cleaning to run the Complete System Clean again. Always leave a tube of water...

Guava® Instrument Cleaning Fluid (ICF) Package Insert 4. Click Main Menu to return to the CytoSoft™ main menu or click Exit to close CytoSoft. NOTE: If you want to continue with data acquisition, launch the desired CytoSoft application and allow the laser to warm up for 5 minutes before resuming data acquisition. 5. Leave a tube of deionized (DI) water on the Guava PCA. Clean the Guava® easyCyte™ Mini System 1. Click Clean and Shut Down from the main menu. The Guava® Clean screen appears. Click Clean Only or Clean and Shut Down. a. Load a tube containing Guava Instrument Cleaning Fluid (ICF)...

Guava® Instrument Cleaning Fluid (ICF) Package Insert Click Quick Clean. Follow the prompts and load a tube containing Guava® ICF or Guava ICF with 10% bleach. Click OK. The cleaning solution runs for approximately 30 seconds. 4. Load a tube containing deionized (DI) water, then click Quick Clean again. 5. Verify that the deionized (DI) water tube is loaded, and then click OK to rinse out the cleaning fluid. Repeat as necessary to remove the clog. Clean a Clogged Flowcell for High-Throughput (HT) (Automated Instruments) If a sample in an automated instrument seems to be running slowly, pause...

Guava® Instrument Cleaning Fluid (ICF) Package Insert If a clog is difficult to clear using Quick Clean, perform a Backflush, then repeat the Quick Clean several times using Guava Instrument Cleaning Fluid (ICF) and deionized (DI) water. If the flow rate is still slow, perform a Complete System Clean procedure until the acquisition rate is normal. If Guava Check, easyCheck, or System Check shows a low particles/mL count and the scatter and fluorescence intensity results are normal, partial clogging is likely. Run Quick Clean using Guava ICF and again with DI water. If the acquisition rate is...

Guava® Instrument Cleaning Fluid (ICF) Package Insert © 2020-2021 Luminex Corporation. All rights reserved. No part of this publication may be reproduced, transmitted, transcribed, or translated into any language or computer language, in any form or by any means without prior express, writ-ten consent of Luminex Corporation. Luminex Corporation (Luminex) reserves the right to modify its products and services at any time. This guide is subject to change without notice. Although prepared to ensure accuracy, Luminex assumes no liability for errors or omissions, or for any damages resulting from...