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UP.SIGHT

UP.SIGHT

UP.SIGHT

Product catalog summary
Overview: The document introduces the UP.SIGHT, a cutting-edge solution for cell line development (CLD) that ensures high clonality and efficiency in single-cell cloning workflows. It combines advanced imaging and dispensing technologies to streamline processes and enhance outcomes.
Key Features:
  • Double Assurance of Clonality: Utilizes two independent methods—nozzle imaging and 3D Full Well Imaging—to ensure monoclonality with a probability of >99.99%.
  • Integrated Workflow: The UP.SIGHT offers an all-in-one solution from single-cell isolation to colony tracking, reducing manual labor and time.
  • Cross-Contamination Prevention: Features the EASY.ON cartridge, designed to prevent cross-contamination and ensure cell viability.
  • Enhanced Imaging and Processing: Combines single-cell dispensing technology with high-quality imaging for faster processing and higher yields.
  • Cell Focusing Technology: Aligns cells for better detection and reduced cell loss, particularly beneficial for rare cell types.
Technical Specifications:
  • Dimensions and Weight: 635 x 400 x 282 mm, 40 kg.
  • Power and Voltage: Approximately 200 W, 100-240 Vac.
  • Imaging Capabilities: Nozzle imaging with 0.81 MP CMOS camera, 10x magnification, and 3 µm resolution; Well imaging with 13.4 MP CMOS camera, 5x magnification, and 2.2 µm resolution.
  • Processing Times: Single-cell dispensing into 96-well plate takes ~2 min, and into 384-well plate takes ~8 min. Full well imaging for 384-well plate takes ~25 min.
  • Compatibility: Automation-ready, compatible with standard biosafety cabinets class 2, and certified CE, CB, UL (TÜV), RoHS.
Contact Information: For more details, contact via email at [email protected] or visit cytena.com/up.sight. Phone numbers for EU and US are provided.
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Catalog excerpts

UP.SIGHT-1

The ultimate upgrade in cell line development

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UP.SIGHT-2

Elevate your cell line development workflow The UP.SIGHT streamlines cell line development (CLD) workflows by automating labor-intensive and time-consuming steps. We have combined our patented, highly efficient, fast and gentle single-cell dispensing technology with a superfast, high-quality imaging system that provides a full well image and no need for image stitching. Our all-in-one solution enables nozzle imaging and 3D Full Well Imaging for double assurance of clonality from two independent optical apparatuses, leading to a probability of clonality >99.99%. Researchers can also bypass centrifuging...

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UP.SIGHT-3

Reducing the risk of cross-contamination The UP.SIGHT’s exclusive EASY.ON cartridge was precisely engineered by microfluidic experts to ensure cell viability with the gentlest handling. The ability to dispose of the cartridges eliminates the risk of cross-contamination between samples. Plus, setting up your experiments has never been easier as the EASY.ON cartridge is magnetically mounted for quick and easy loading. All-in-one single-cell cloning solution, from single cell to colony With an integrated imager, the UP.SIGHT enables a full single-cell cloning workflow in one instrument. From gentle...

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UP.SIGHT-4

Higher yields, greater insights and faster processing The UP.SIGHT combines our patented single-cell dispensing technology with an industry-leading imaging system for improved single-cell cloning workflow, enabling higher clonal yields and faster processing speeds. The instrument’s operating software analyzes cell morphology to isolate single cells according to set parameters such as size, roundness and even fluorescence intensity (if working with fluorescent cells). The quick and intuitive setup of thresholds for each parameter ensures that only desired cells are dispensed into wells in order...

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UP.SIGHT-5

Cell Focusing - Minimizing cell loss Add an additional layer of optimization with Cell Focusing technology, which gently aligns cells at the center of the dispensing cartridge for superior cell detection. It offers significant improvements when working with rare cell types as this alignment ensures that cells and their morphology are perfectly captured and measured, reducing cell loss and even increasing processing speeds.

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UP.SIGHT-7

Technical Specifications File type (JPEG) Camera CMOS, 0.81 MP Nozzle imaging Magnification 10x Optical resolution 3 µm Excitation wavelength 488 nm Emission wavelength 520 +/- 36 nm File type (JPEG) Well imaging Camera CMOS, 13.4 MP Magnification 5x Optical resolution 2.2 µm Single-cell dispensing into 96-well plate: ~2 min Single-cell dispensing into 384-well plate: ~8 min Processing times Single-cell dispensing plus 3D Full Well Imaging 384-well plate: ~25 min Well bottom imaging of 96-well plate: ~8 min Well bottom imaging of 384-well plate: ~8 min Embedded computer (Win 10 x 64 Prof.) Automation-ready...

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UP.SIGHT-8

Email: [email protected] | Web: cytena.com/up.sight EU Phone: +49 761 70 88 90-0 | US Phone: (+1) 833-235-5465

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All Cytena GmbH catalogs and technical brochures

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  4. F.SIGHT 2.0

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.