112PP
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PRESSURE MYOGRAPH SYSTEM - 112PP Ergonomic design to facilitate easy and quick mounting of arteries Low volume of chamber fluid to minimize amount of reagents Pulsatile flow studies with pulse rates between 50 and 600 per minute. The Pressure or Perfusion Myograph System – 112PP is a system used to study the structure and function of isolated sections of small vessels (diameter >40 μm) under near physiological conditions. Vessel diameters can be measured in response to pharmacological and physiological stimuli. In addition the system allow simulation of pulsations between 50 and 600 BPM with a pressure difference up to 60 mmHg. A built-in heating system maintains the chamber temperature, eliminating the need for continuous and often costly super fusion. The chamber cover includes ports for super fusion, for rapid draining and filling, for cumulative addition of drugs and for oxygenation. To facilitate cleaning, the chamber is made of acid resistant stainless steel. Measurements are continuously recorded by a computer with dimension analysis software - MyoVIEW. As an option, the FlowMeter - 162FM can be added to the system to measure flows between 15 - 4000 μl/min. Flow cannot be measured during pulzation Because of the nature of the technique, physiological responses such as the myogenic response and flowmediated dilation can be examined. The state of the art Pressure Myograph software MyoVIEW will collect data such as vessel wall thickness, changes in vessel and lumen diameter, intra vascular pressure, and a host of other calculated parameters, such as shear stress and vascular resistance, can be collected, setting pressure or perfusion myography apart from standard organ bath techniques. The Acquisition & Analysis Package The DMT Inverted Microscope, inverted Zeiss, Nikon or similar microscopes (contact DMT for further specifications) with USB camera, computer and data acquisition software

PRESSURE MYOGRAPH SYSTEM - 112PP CHAMBER: Chamber volume (min) Chamber(s) Chamber material Vessel size Vessel alignment Micrometer resolution Mounting type Pulse rate TEMPERATURE: Range Resolution Stability Heating TRANSDUCER FORCE: Output reading Range Resolution Force calibration TRANSDUCER PRESSURE: Output reading Range Pressure stability Resolution Force calibration RESERVOIR: Heated Capacity Pressure circuit Air inlet OUTPUT: Data communication Analogue output channels Analogue output range