840MD
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Catalog excerpts

840MD - 1

MyoDYNAMICS MUSCLE STRIP MYOGRAPH SYSTEM - 840MD • For use with skeletal and cardiac muscle and strips of other muscle types up to 30 mm in length Programmable motor for stretching/retracting a mounted muscle 10 µm up to 11 mm Simultaneously examine up to four muscle strips under isometric conditions. Eccentric contraction for e.g. fatigue studies Individually built-in heating, oxygen and suction ports Water cooling circuit allowing working temperatures below room temperature Force output is available as direct analog signal output Compatible with the DMT Stimulator - CS4/CS8 Optional add-on Automatic Buffer Filler System - 625FS allowing semi-automated filling of all chambers The MyoDynamics Muscle Strip Myograph System - 840MD represents a state-of-the-art 4-channel Myograph System for muscle strips of up to 30 mm in length. The system was originally developed to give the skeletal muscle physiologist a precise, easy-to-use, high-throughput muscle myograph with the capacity to stretch and retract the muscle under a range of conditions including electric field stimulation. The special design of the chamber, however, gives this system the flexibility to mount larger muscle strips of various organs and striated muscle up to 30 mm. Each muscle bath unit, made of aluminium, features a stainless steel chamber. The tissue supports are positioned in the chamber with one side attached to the force transducer and the other to a combination manual positioner screw and a motorized micropositioner. The manual positioner allows the accurate setting of pre-load while the motorized micropositioner permits the user to stretch/relax the muscle according to user-defined settings. The sensitive force transducers provide measurement of isometric muscle contractions. Mounted tissue can be stretched and relaxed as defined by the user with a minimum distance of 10 µm up to 11 mm and a maximum speed of 12 mm/sec. The 840MD system is perfect for eccentric contraction studies. The Myograph comes with a unique tissue clamp system and hooks to hold the mounted tissues. Customized mounting supports can be made upon request. Stimulation electrodes built into the chamber cover (optional) can be used to activate the muscle via field stimulation from DMT Stimulator’s CS4 or CS8. This Myograph is well suited for studies involving muscle reactivity and fatigue experiments in connection with neuromuscular disorders such as muscular dystrophy, ataxia and myofibrillar myopathies. Multiple units, especially when supplemented with the Automatic Buffer Filler System - 625FS, can be arranged side-by-side to facilitate high-throughput screening, such as drug testing or for experiments requiring the separation of muscle preparations i

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840MD - 2

MyoDYNAMICS MUSCLE STRIP MYOGRAPH SYSTEM - 840MD SPECIFICATIONS: Chamber Chamber suction Chamber cover Chamber gassing Chamber size Chamber material Chamber temperature range Force range Force resolution Max. segment length Min. segment length Max. micrometer reach Max. micrometer step Motor speed Resolution Speed tolerance Min. resolution of motor Distance tolerance Motor control Analogue outputs Analogue output range Output impedance Digital input Voltage range Digital output Air Connection Four individual chambers Manual or automatic Supplied with connections for gassing Individually...

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