WIRE MYOGRAPH SYSTEMS Vascular research • Airway research • Intestine research • Urinary and bladder research • Gall bladder research • Gut research • Erectile dysfunction •

The Wire Myograph allows examination of small vessels (internal diameter 30 pm - 10 mm) in terms of morphology and responsiveness to hormones and other agonists. The small vessels are mounted as ring preparations by threading them onto two stainless steel or tungsten wires and securing the wires to two supports. One support is then attached to a micrometer, allowing control of vessel circumference. The other support is attached to a force transducer for measurement of tension development. The whole preparation is kept in a chamber with physiological salt solution at 37°C, bubbled with oxygen....

WIRE MYOGRAPH SYSTEMS - PRODUCTS SINGLE WIRE MYOGRAPH SYSTEM - 320A The Single Wire Myograph System – 320A is an ideal single chamber wire myograph system for measuring contractile force measurements in vessels with diameters of 30um – 3mm. • • • Manually operated micropositioner for accurate tension control Can be easily combined with microelectrodes for membrane potential measurements Easily integrates into an imaging system for simultaneous force measurements and vessel wall fluorescence DUAL WIRE MYOGRAPH SYSTEMS - 420A & 520A The Dual Wire Myograph System - 420A & 520A is designed for simultaneous...

CONFOCAL WIRE MYOGRAPH - 360CW The Confocal Wire Myograph System - 360CW is specifically designed to provide very close optical access to the mounted artery or tissue segment, thereby allowing high resolution images of fluorescent dyes or markers by laser scanning confocal microscopy (LSCM). • • • • • For use with small vessels or ring shaped tissues from 30 μm - 3 mm, inverse mounted on special jaws For fluorescence or high-end morphological imaging Sandwich bath design enables use of very low working distance objectives Conical chamber to facilitate very low media volume. Hinged top facilitates...