CATALOGUE T he blood matching company

What is the outlook for DIAGAST ? DIAGAST is a French company developing its blood-matching expertise and know-how in international markets. We offer ranges of high-performance products and services, guaranteeing the quality of transfusion diagnostics and patient safety. Faced with competition from international groups, our strength lies in our ability to react flexibly and to continuously offer creative solutions, thanks to the commitment of our multicultural workforce. This source of innovation is the result of our expertise and technological knowhow. DIAGAST has been developing a culture of...

CONTACT DIAGAST DIAGAST headquarters 251, avenue Eugène Avinée - 59120 LOOS - FRANCE Tel. : +33 (0)3 20 96 53 53 - Fax : +33 (0)3 20 96 53 54 - [email protected] DIAGAST Ibérica S.L. Soberanía 2, 2°A - 28260 Galapagar (MADRID) Antonio Campos - Tel. : (+34) 91 858 38 88 - [email protected] DIAGAST India D-304, Sushant Shopping Arcade - Sushant Lok I - GURGAON 122001 Haryana Mr. Rajeev PANT - [email protected] Tel. : + 91 124 4255351 - Fax : +91 124 4255355 International hotline and after sales services [email protected] - Tel. : +33 (0)3 20 96 53 65 www.diagast.com Please visit our website...

MANUAL RANGE QUALITY CONTROLS BEDSIDE CARD TRAINING CENTRE

DIAGAST training centre

AUTOMATED SYSTEMInstrument Designation Reference Description QWALYS® Connect 90860 1 Unit Middleware for the remote consultation & validation of tests performed on QWALYS® QWALYS® Connect is the right solution for multi-sites, multi-QWALYS® laboratories. QWALYS® Connect is a complete data management solution for monitoring single or multiple QWALYS® systems : • data concentration, • real-time data backup and storage, • multi-LIS connection management, • real-time communication between QWALYS® systems, • remote access application to consult, modify and validate results. Unit Unit Units Units Unit Unit Unit Unit Unit Unit Unit Unit Unit Unit Unit...

Grouping and Phenotyping Patient Red Blood Cells (RBC) Bromelin Magnetic particles (MagneLys) Predispensed monoclonal IgM antisera 1% dilution of RBC in bromelin and MagneLys. Dispensing in the microplate Shaking: rehydration of antisera and contact with RBC antigens Incubation at room temperature Predispensed monoclonal IgM antisera Magnetization: Attraction of RBC by magnetic field to the bottom of the well Shaking Magnet Positive reaction: Agglutination Negative reaction: No Agglutination

ANTIGENS DETECTION *On subscription ** Manufacturing on request Grouping and Phenotyping Ready-to-use reagents on microplates Designation Reference DuoLys 79960 12 microplates of 8 tests, MagneLys 40 mL 10 microplates of 16 tests, MagneLys 40 mL Groupa 2 Lys 79964 12 microplates of 8 tests, MagneLys 40 mL 12 microplates of 8 tests, MagneLys 40 mL 12 microplates of 8 tests, MagneLys 40 mL 12 microplates of 16 tests, MagneLys 40 mL 12 microplates of 8 tests, MagneLys 40 mL Reverse Typing Red Blood Cells* Magnetized red blood cells A1, A2, B and O (4 x 5 mL) Diluents BROMELINE 69024...

Weak-D and Antigens Typing Patient RBC magnetized «on board» with IRONMAG Antisera (Anti-D WEAK, Anti-Fya, Anti-Fyb, Anti-Jka,Anti-Jkb, Anti-S, Anti-s) NanoLys Magnet Antisera RBC magnetized with IRONMAG NanoLys Incubation at 37°C: Antisera bind to RBC Antigens Magnetic shaking: Magnetic field + shaking. The magnetized RBC cross the NanoLys (high density barrier): no influence of magnetic field on free antibodies that remain blocked at the surface on NanoLys. No washing step. Positive reaction: Layer Antibodies fix the corresponding antigen on the magnetized RBC: Reaction with AHG. Negative reaction:...

ANTIGENS DETECTION Weak-D test Ready-to-use reagents on microplates Designation Reference Quantity Weak-D kit includes QR Anti-D weak (2040!) AND QR NEG CONTROL (20507) Qr Anti-D weak 20401 1 x 3.5 mL Antigens recognition diagram of Qr Anti-D weak clones

Serum or plasma ScreenDiluent NanoLys Magnet AHG: Anti-IgG or Anti-IgG + Anti-IgM Unspecific antibody Unexpected antibody HEMASCREEN (premagnetized RBC) NanoLys Incubation Antibodies bind to HEMASCREEN antigens Magnetic shaking: Magnetic field + shaking. The HEMASCREEN cross the NanoLys (high density barrier): no influence of the magnetic field on unspecific antibodies. The unspecific globulins remain blocked at the surface of the NanoLys. No washing step Positive reaction: Layer Unexpected antibodies fixed on HEMASCREEN: Reaction with AHG. Negative reaction: Clear dot No unexpected antibodies: No reaction...

INDIRECT ANTIGLOBULIN TESTSAntibody Screening (A.B.S.) Ready-to-use reagents on microplates Reference Quantity 6 AHG anti-IgG coated plates NanoLys (7 x 8 mL), ScreenDiluent (50 mL) 48 tests - Identification 192 tests - Antibody Screening 576 tests - Donor Antibody Screening Pool of magnetized red blood cells HEMASCREEN 59852 3 x 4.5 mL Panel of 3 magnetized red blood cells HEMA-IDENT 59855 11 x 4.5 mL Panel of 11 magnetized red blood cells Reagents NanoLys ScreenDiluent IRONMAG

Crossmatch Patient recipient’s serum or plasma Donor’s RBC magnetized «onboard» with IRONMAG AHG: Anti-IgG + Anti-IgM NanoLys Magnet Unspecific antibody Unexpected or natural antibody Donor’s RBC NanoLys Incubation at room temperature and 37°C Antibodies bind to donor’s RBC Magnetic shaking: Magnetic field + shaking. The magnetized donor’s RBC cross the NanoLys (high density barrier): no influence of the magnetic field on unspecific antibodies that remain blocked at the surface of the NanoLys. No washing step Positive reaction: Layer Recipient’s antibodies fix donor’s RBC: Reaction with AHG. Do not...

INDIRECT ANTIGLOBULIN TESTS Ready-to-use reagents on microplates Designation Reference 8 AHG anti-IgG and anti-IgM coated plates DiluentLys 69301 12 dilution plates (48 dilutions /plate) IRONMAG 20000 Blood segment device