Verdye (indocyanine green) fluorescence dye

Product catalog summary

Overview: Verdye, also known as Indocyanine Green (ICG), is a diagnostic fluorescence product used globally by physicians to guide treatment procedures. It is primarily used in ophthalmic angiography, cardiac, circulatory, micro-circulatory diagnostics, and liver function diagnostics.

Key Features:

Well tolerated with an excellent safety profile.
Cleared exclusively through the liver with a half-life of 3-4 minutes.
Rapidly binds to plasma proteins and undergoes no significant extrahepatic or enterohepatic circulation.

Approved Indications:

Ophthalmic Angiography: Measurement of choroid perfusion.
Cardiac and Circulatory Diagnostics: Measurement of cardiac output, stroke volume, and circulating blood volumes.
Liver Function Diagnostics: Measurement of liver excretory function.

Chemical Description: Verdye is a tricarbocyanine dye with the empirical formula C43H47N2NaO6S2, appearing as a green powder.

Dosage and Administration:

Available in 25mg and 50mg vials, depending on the territory.
Dosage varies based on indication and patient weight, with specific guidelines for adults, elderly, adolescents, and children.
Must be dissolved in water for injection and used immediately after reconstitution.

Contraindications and Side Effects:

Contraindicated in patients with hypersensitivity to indocyanine green, sodium iodide, or iodine, and those with thyroid issues.
Not recommended for premature babies and newborns with hyperbilirubinaemia.
Very rare side effects include nausea and hypersensitivity reactions, with a higher risk in patients with severe kidney failure.

Worldwide Registration and Distribution: Verdye is registered and distributed in numerous countries across Europe, Asia, the Americas, and other regions.

Contact Information: For reporting adverse reactions or product compliance issues, contact Diagnostic Green GmbH via email or phone.

Catalog excerpts

Verdye (indocyanine green) fluorescence dye-1

Verdye (Indocyanine Green) Diagnostic Green’s Indocyanine Green (ICG), Verdye is the leading fluorescence product trusted by physicians worldwide, to guide their treatment procedures, based on fluorescence.

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Verdye (indocyanine green) fluorescence dye-2

APPROVED INDIC ATIONS Ophthalmic angiography diagnostics Cardiac, circulatory & micro-circulatory diagnostics  Measurement of perfusion of the choroid  Measurement of cardiac output and stroke volume  Measurement of circulating blood volumes Liver function diagnostics  Measurement of excretory function of the liver  Measurement of cerebral perfusion Chemical Description: Tricarbocyanine Dye  Excellent safety profile** Appearance: Green powder  Cleared exclusively through the liver  Half-life of 3-4 minutes  Rapidly bound to plasma protein  Undergoes no significant extrahepatic or enterohepatic...

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Verdye (indocyanine green) fluorescence dye-3

HOW IT IS SUPPLIED Active Substance: Indocyanine Green (ICG) Package configuration: ICG Pharmaceutical Product is available in packs of 5 vials Drug Content: Vials are available in 25mg and 50mg, depending on territory ICG Pharmaceutical Product is a Prescription Only Medicine (POM) CONDITIONS OF USE AND STOR AGE  Storage: See Product Information Leaflet (PIL) for storage instructions  Under sterile conditions, the Indocyanine Green Diagnostic Product, Verdye should be dissolved with water for injection  Once reconstituted, the solution must be used immediately  Sterile product, intended...

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Verdye (indocyanine green) fluorescence dye-4

WORLDWIDE REGISTR ATION & DISTRIBUTION Currently registered for distribution           Austria Belgium Canada Chile Croatia Czechia Denmark Finland Germany Hungary Israel Ireland Italy Malta Mexico Netherlands Poland Portugal Romania Russia Spain Slovenia Sweden UK Ukraine USA Supplied under exemption            Armenia Australia Bahrain Baltic States Belarus Bosnia Bulgaria Croatia Cyprus Georgia Hungary Iceland Kazakhstan Lithuania Luxembourg Morocco New Zealand Norway Oman Philippines Kuwait Saudi Arabia Serbia Singapore Slovakia Sri Lanka South Africa Switzerland Thailand...

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