Espion Profile Multifocal The Espion multifocal ERG system software and hardware has been developed by Diagnosys LLC to provide an easy to use clinical system for combined spatial and temporal information on retinal function. The default 61 and 103 elements (max 243 elements) are available with both short and long M-sequences.The full M-sequence test takes 8 minutes to perform with variable configurable segments lengths. Stimulus features • Both eyes can be tested simultaneously • Ultra-wide field stimulus (90 degrees) • Variable size, scale and type of stimulus: Hexagonal/dartboard/square stimulus patterns • Extendable stimulus period using filler frames • Variable size, location and color of fixation cross • Variable M-sequence length tailored to hex count • Testing can be stopped periodically to rest the patient Hardware features • 5 Channel headbox with industry-first 32-bit amplifiers • 32" LCD wide angle monitor custom-designed to minimize luminance artifact and electrical noise • Brightness 1000 cd/m2, Contrast ratio 1000:1 • Integrated Power Supply Isolation Unit • 3 system configurations: Stand-alone, cart-mounted with power lift table (shown right) Stand-alone, bench-mounted (overleaf) or integrated into the Espion System

Headbox features • 5 isolated channels can be acquired simultaneously (32 bit ADC) • Low pass and high pass filtering • Digital filtering when processing signal Software features • Full integration with Espion software • Easy setup of multifocal protocols • Print preview and customizable print layout templates • Export data Optional Infra-red Camera Infrared fixation camera tracks fixation and automatically Run-time features interrupts testing when fixation deviates by a pre-determined • Real time trace display during testing • 50Hz/60Hz mains removal option • Noise level monitoring • Adjustable...

Espion Profile VEP and PERG Optional VEP and PERG round out the Espion Profile multifocal system to create an ideal instrument for neuro-ophthalmology applications. The large, bright screen coupled with the 32-bit acquisition system produces VEP and PERG responses of unprecedented clarity. The screen has been highly engineered to minimize the luminance artifact that makes most LCD screens unsuitable for use as VEP stimulators. Stimulator Features • Calibrated luminance and color • Max resolution of 1366 x 768 • 75 Hz Frame Rate • 6 bit Color/luminance control • Luminance > 1000 cd/m2 • Checkerboards,...

Data Acquisition The data acquisition system is based around a fast DSP microprocessor that controls and synchronizes data acquisition and stimulator timing independently from the PC. The system is comprised of 5 differential DC coupled amplifiers (prevent AC amplifier lockup) with the following specification: • Industry-first 32 bit resolution (<1nV LSB) • Fully isolated • Input range +/- 2.5V max; +/-625 mV default • Automated internal calibration • Integral anti-alias filter • Differential channel input gain matching better than 0.01% • Ultra low noise <1uV RMS • Input impedance greater than...