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When the cellular oxygen level is low or mitochondria are not working properly, energy production switches to a less efficient anaerobic modus. In this modus the primary by-product is lactate. Lactate is transported to the liver and metabolized there. Normally the liver breaks down lactate immediately, therefore its level stays within the normal range. In case of shock, sepsis and burn injuries lactate level increases and serves as a prognostic marker in intensive care units and emergency rooms. Furthermore lactate is determined in neonatal care units to control oxygen supply in newborn and premature...