OIL EXTRACTION FOR GRAVIMETRIC ANALYSIS Millmix 20, Centric 350 MAIN FEATURES: > Low sample deviation > References from Pharmaceutical industry > Efficient sample preparation solution Sample preparation solution - with MILLMIX 20 & CENTRIC 350 is developed for pharmaceutical industry. - oil extraction from fermentation broth for gravimetric analysis MILLMIX 20 Grinding adaptor Time & Speed References This method is used in NOVARTIS Group Sample preparation for gravimetric analysis at all fermentation processes in pharmaceutical industry We reserve the right to alter specification details etc. without prior notice or liability! DOMEL, d.o.o., Otoki 21, 4228 Železniki BU Laboratory Systems, Na Plavžu 79, 4228 Železniki Phone: +386 4 5117 500 Fax: +386 4 5117 501 WEB: http://labs.domel.com E-mail: [email protected]

TEST REPORT Report No.: Date: Contact: Ref. file: TASK: Application field: Oil in fermentation broth (clavulanic acid) Feed size: 30 g homogenized fermentation broth mixed with 30 ml n-pentan Feed quantity: Material specification: fermentation broth, wet material Customer requirements: Subsequent analysis: SOLUTION: Configurations: 50 ml FALCON tube (shaking 4 tubes at the same time) Achieved results: reproducible and reliable results Remarks: Measurements can deviate from achieved results above mentioned, depending on differences in materials. This report could be used as a reference to help...

Lek d.d.AI Proizvodnja Lendava I©fC Lek Farmacevtska druzba d.d. clan skupine Sandoz Proizvodnja Lendava Enota Kakovost Ekstrakcija olja iz fermentacijske brozge klavulanska kislina Izdelal: Brigita Kaucic Krhac podpis datum Namen raziskave je potrditi, da aparat Millmix 20 proizvajalca Tehtnica ustrezno ekstrahira olje iz fermentacijske brozge klavulanske kisline in da so rezultati vsebnosti olja v fermentacijski brozgi dobljeni z stresanjem term.brozge na aparatu Millmix 20 primerljivi z rezultati vsebnosti olja, ki so dobljeni z rocnim stresanjem. Vsebnost olja v fermentacijski brozgi klav.kisline...