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Inhalation and Exposure brochure

Inhalation and Exposure brochure

Inhalation and Exposure brochure

Product catalog summary
Overview of Inhalation Tower
DSI’s Buxco Inhalation Tower is designed for uniform exposure of mice and rats to aerosols, gases, and dusts. It features a compact, 'flow past' concentric design with 14 exposure ports, ensuring each animal receives the same exposure. The tower is constructed from aluminum for ease of handling, with a stainless steel version available. It includes low dead-space nose adapters, support pins for heavier animals, and can be configured for slight positive or negative pressure environments.
Key Features
  • Concentric 'flow past' design for uniform exposure.
  • Top and bottom ports for versatile delivery options.
  • Easy disassembly for cleaning.
  • Flexible base design options.
  • Aluminum and stainless steel construction options.
Single Subject Exposure Station
The Buxco Single Site Exposure Station is a cost-effective, single-port device for nose-only exposure, suitable for one subject at a time. It is compatible with nose-only restrainers and plethysmographs, and is available for both mice and rats. The station features a low dead space exposure area and uses the Aerogen Aeroneb® nebulizer for aerosol delivery.
Recommendations
  • Use exposure restrainers or plethysmographs with AllayTM restraints to ensure natural breathing and reduce acclimation time.
  • For single subject exposure, use the single subject exposure equipment.
Mass Dosing Chambers
The Mass Dosing Chamber is designed for administering aerosol or gas to multiple subjects simultaneously. It features a perforated floor for urine drainage, a removable lid, and multiple ports for aerosol or gas delivery. The chamber can accommodate approximately 15 mice, 6 rats, or 2 guinea pigs, while the larger version can hold 25 mice, 10 rats, or 4 guinea pigs.
Features
  • Perforated floor for drainage.
  • Removable lid for use inside a containment hood.
  • Multiple ports for delivery and bias flow.
Usage
For precise nose-only exposures, the Inhalation Tower system is recommended. The Mass Dosing Chamber should be used when general dosing is acceptable, and it can be controlled with the Mass Dosing Aerosol Controller or a custom setup.
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Catalog excerpts

Inhalation and Exposure brochure-1

Inhalation Tower Better Data. Better Science. DSI’s Buxco Inhalation Tower is a compact, “flow past” design, with fourteen (14) exposure ports for mice and rats. The Inhalation Tower features: • “Flow past” concentric design, so each animal receives the same exposure Top and bottom ports, for delivering aerosols, gases and dusts Low dead-space nose adapters Easy disassembly for cleaning Flexible base design options Aluminum construction for ease of handling. Stainless steel version also available. Support pins for securing heavier animals This tower can be used in slight positive or slight negative pressure configurations Inhalation Tower (stainless steel) Inhalation Systems can be outfitted with a variety of delivery and instrumentation options for challenge and environmental monitoring. We recommend using our exposure restrainers or plethysmographs with patented AllayTM restraints. Allay restraints secure the animal without compressing its thoracic cavity or otherwise affecting the animal’s respiration, making the animal’s breathing more natural and reducing acclimation time. For delivery to only one subject at a time, use the single subject exposure equipment. Single Subject Exposure DSI’s Buxco Single Site Exposure Station is a single port nose-only exposure device. A cost-saving version of the Inhalation Tower, which allows uniform exposure, one subject at a time. • Use with nose-only restrainers and plethysmographs Available for mice and rats Low dead space exposure area

 Open the catalog to page 1
Inhalation and Exposure brochure-2

Mass Dosing Chambers DSI’s Buxco Mass Dosing Chambers are used to expose multiple subjects to an aerosol or gas when general dosing can be tolerated. For precise nose-only exposures, use the Inhalation Tower system. Use with the Mass Dosing Aerosol Controller to control the nebulizer, or generate your own. A separate bias flow supply may be needed. Features • A perforated floor for urine drainage • A removable lid (no seal, should be used inside a containment hood) • Two ports for aerosol or gas delivery • Four Luer ports for bias flow or other use Use the Mass Dosing Chamber and Controller,...

 Open the catalog to page 2
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.