pft

pft

Product catalog summary
Pulmonary Function Testing (PFT) Overview
Pulmonary Function Testing (PFT) offers a comprehensive assessment of lung function, ideal for studies on chronic obstructive pulmonary disease (COPD). The system allows for a series of tests to be completed in minutes with immediate results, facilitating the comparison of repeated tests through overlays.
Key Features and Capabilities
  • Determines functional residual capacity (FRC) and other lung capacities.
  • Software reports include forced expiratory volume (FEV), forced expiratory flow (FEF), and other critical values.
  • Direct measurement of pulmonary mechanics, including lung resistance and dynamic compliance.
  • Reports provide group averages of pressure-volume (P-V) loops and flow-volume (F-V) loops.
Applicable Subjects
The system is suitable for use with mice, rats, guinea pigs, and non-human primates (NHP). Custom chambers for additional species may be available upon request.
Testing Procedures
  • Similar to spirometry in cooperative humans, the PFT system provides comprehensive data for preclinical applications.
  • For FRC tests, subjects must be spontaneously breathing. Other tests can be conducted with ventilated or spontaneously breathing subjects, who are anesthetized for automated testing.
System Components
  • The PFT system includes a controller, calibrator, and chambers, along with a control panel featuring pressure/vacuum reservoirs and a plethysmograph.
Available Tests
  • Boyle’s Law FRC
  • Fast Flow Volume
  • Quasistatic Pressure Volume
  • Resistance and Compliance analysis
Data Presentation
An FV Loop report can display results from two different groups on the same graph, enhancing data comparison and scientific analysis.
Conclusion
The PFT system provides better data for better science, supporting detailed pulmonary function analysis in preclinical research.
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Catalog excerpts

pft-1

Pulmonary Function Testing (PFT) Features • Most comprehensive assessment of the lung • Complete a series of tests in just minutes • View results immediately, use overlays to compare repeated tests Better Data. Better Science. Similar to spirometry in cooperative humans, the pulmonary function testing system provides comprehensive PFT data for preclinical applications. For the functional residual capacity (FRC) test, subjects must be spontaneously-breathing. For other tests, subjects may be ventilated (ventilator included) or spontaneously-breathing. Subjects are anesthetized, and the tests are automated. • Ideal for chronic obstructive pulmonary disease (COPD) studies • Determine FRC and other lung capacities • Software reports forced expiratory volume (FEV), forced expiratory flow (FEF), and many other values • Direct measurement of pulmonary mechanics - lung resistance and dynamic compliance • Reports produce group average of P-V loops and F-V loops PFT controller, calibrator, and chambers. The PFT system includes a control panel with pressure/vacuum reservoirs, and plethysmograph. Available for: Mice, Rats, Guinea Pigs, and NHP. Additional species or custom chambers may be available upon request. Available Tests: • Fast Flow Volume Quasistatic Pressure Volume Resistance and Compliance analysis is also available. An FV Loop report showing the results of two different grou

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