Rodent Social Housing Telemetry Improving animal welfare is of utmost importance to the preclinical research community. Animal Welfare guidelines1 and directives2 recommend social housing whenever possible to benefit overall animal well-being. In addition, research shows that pair-housing can reduce stress artifacts in physiologic data3,4. Social species thrive when housed in an environment that mimics their natural environment as closely as possible. DSI offers social housing solutions for research studies involving animals from mice to non-human primates. The HD-S11 and HD-S1 support pair housing in small animal models (e.g. rats and similar sized animals) where cardiovascular endpoints are needed. Researchers can now simultaneously collect pressure, biopotential (HD-S11 only), temperature and activity data continuously and in real-time from two small animals in a single cage using PhysioTel HD-S11 or HD-S1 implants with DSI's RPC-3 receiver. HD-S11 and HD-S1 allow researchers to conduct study designs such as: • Behavioral studies • Chronic stress exposure • Comparison of drug effects in single vs. pair housed animals • Acute stress response 3 months 18 MHz 1 pressure, temperature, and activity Battery Life 2 months 3 months 2 months temperature, temperature, and activity and activity and activity 119 14th Street NW, Suite 100, St. Paul, MN 55112 www.datasci.com Copyright © 2016 Data Sciences International

Neuroscience Telemetry Solutions With the 4ET implant, researchers can simultaneously and continuously collect four biopotential signals in numerous combinations to record EEG, EMG, EOG or ECG, in addition to temperature and activity, from two animals in a single cage. The 4ET is sized to be used in rats and similar sized animals with DSI’s RPC-2 receiver. Telemetric recording of physiologic data coupled with automated sleep-wake scoring and seizure detection software facilitates the understanding of the following: M series and L series. • • • • • Neurobiological regulation of sleep homeostasis...