1. Catalogs
  2. Eckert & Ziegler
  3. I-125 Ophthalmic Seeds
video corpo

I-125 Ophthalmic Seeds

I-125 Ophthalmic Seeds

I-125 Ophthalmic Seeds

Product catalog summary
Introduction
IsoSeed® I25.S16 is a brachytherapy source used for treating eye tumors such as uveal melanomas and retinoblastomas. It offers a wide range of apparent activities up to 25 mCi, making it suitable for medium to large tumors, providing an alternative to Ru-106 Eye Applicators.
Application
IsoSeeds® I25.S16 are delivered non-sterile and can be inserted into Plaque Shells. After steam sterilization, the assembled Applicator is ready for use.
Calibration
The source strength is certified based on air kerma measurements traceable to the PTB and NIST standards, ensuring accuracy and reliability.
Biocompatibility and Quality
The titanium capsule meets ASTM F67 requirements for biocompatibility. Manufactured in Germany, each seed undergoes rigorous quality checks, and the company is ISO 13485 certified.
Technical Details
IsoSeed® I25.S16 uses iodine-125 with a half-life of 59.41 days, decaying by electron capture and emitting γ-radiation and X-rays. The titanium capsule absorbs emitted electrons.
Source Strength
Each seed's air kerma strength is measured and converted into apparent activity, with a maximum deviation of ±5% from the batch mean.
ISO Classification and Expiration
Classified as C63X11 under ISO 2919, the seeds can be reused for up to 6 months, depending on activity levels.
Activity Classes
The document provides a detailed table of activity classes, specifying air kerma strength, apparent activity in mCi, and MBq for each class, ranging from A01 to A25.
See more

Catalog excerpts

I-125 Ophthalmic Seeds-1

I-125 Ophthalmic Seeds Individual Eye Tumor Treatment Eckert & Ziegler BEBIG’s Ophthalmic Seed is the IsoSeed® I-125 (I25.S16) with a particularly high activity for eye tumor treatments. IsoSeed® I25.S16 is used for the treatment of eye tumors, such as uveal melanomas and retinoblastomas. With apparent activities covering a wide range up to 25 mCi, it is even suitable for treating medium-sized to large eye tumors, opening up treatment options beyond Ru-106 Eye Applicators. The certified source strength is based on air kerma measurements of IsoSeed® which are traceable to the primary standard of the PTB (Physikalisch-Technische Bundesanstalt = National Metrology Institute of Germany). Along with the NIST (National Institute of Standards and Technology), the PTB is a member of the Mutual Recognition Agreement. Application IsoSeeds® I25.S16 are delivered non-sterile. For application, they can be inserted into Plaque Shells. After steam sterilization, the individually assembled Applicator is ready for u

 Open the catalog to page 1
I-125 Ophthalmic Seeds-2

Guaranteed Biocompatibility The titanium capsule of IsoSeed® I25.S16 meets ASTM F67 requirements to ensure biocompatibility of Eckert & Ziegler BEBIG Ophthalmic Seeds. „Made in Germany" Quality The Ophthalmic Seeds are manufactured in Germany in compliance with strict quality standards. Each single item has to pass an individual quality check at every production stage before proceeding to the next step. Eckert & Ziegler BEBIG is certified in accordance with ISO 13485. Source Strength The air kerma strength of every IsoSeed® I25.S16 is measured individually and converted into apparent activity....

 Open the catalog to page 2

All Eckert & Ziegler catalogs and technical brochures

  1. Hot Cell

    7  Pages

*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.