BioPharma Processing
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BioPharma Processing - 1

P R O C ES S I N G Meeting your needs from Laboratory to Fill/Finish fluid transfer | fluid path filtration | testing & analysis process monitoring | labware & supplies 020-8574-7556 Expert product assistance Katie, Application Specialist Find >100,000 products at ColeParmer.co.uk

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BioPharma Processing - 2

Cole-Parmer: delivering accurate, precise fluid handling for biopharmaceutical/pharmaceutical customers for more than 30 years • 100% compliance rate with customer quality audits • 99.7% accuracy on recommended products for customer needs • 3% satisfaction rating among biopharmaceutical 9 customers when doing business with Cole-Parmer • ertificates of material compliance available on more C than 2,000 products. In addition, we offer product lot control, product documentation, animal-derived ingredient documentation, change control notifications, and more to keep you compliant with industry...

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BioPharma Processing - 3

Fermentation At the heart of your process, fermentation creates the proteins for your therapies. Careful monitoring and precise addition of media and other additives are essential for effective growth. Cole-Parmer has what you need for optimal output. Pre-Seed Reaction Vessel Find these products! Look for these key codes in the Table of Contents on page 3 Tu Pump System Vent Filter Seed Reaction Vessel Sample Bottle Harvesting Pump System Production Reaction Vessel Contact us for the full range of products and latest prices! Fax: 020-8574-7543 sales@coleparmer.co.uk www.coleparmer.co.uk

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BioPharma Processing - 4

Harvesting From washing to buffer injection to filtering, the steps in harvesting begin to separate the protein from the cells. Look to our pumps for fluid transfer capabilities as well as single-use lines between filters and vessels. Depending on your production scale, our filtration products may also provide critical performance in your process. Pump Retentate Fermentation Buffer Washing Tank Pump Pump Washing Tank Storage Vessel “Gone are the days when upstream scientists could modify their process and ignore the repercussions in manufacturing.” —Cell Culture World, Congress 2016...

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Purification Separate your final product from all remaining contaminants and effluvia. Concentrate and refine the proteins to prepare them for final product fill/finish. Pressure Sensor Chromatography Pressure Sensor Filtrate Vessel Fill / Finish Other Processes Whether for quality control, process monitoring, research and development, or worker and process environment protection, look to Cole-Parmer for your needs. Can’t find the exact item you need in this catalog? Visit ColeParmer.co.uk for more options! Fluid Transfer Masterflex® L/S® Pumps . . . . 5–13 Process Monitoring Pm Pressure ....

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BioPharma Processing - 6

More @ ColeParmer.com! Fluid Transfer Move fluid with confidence and precision Pumps to meet your exact specifications from development to media preparation to final fill/finish Masterflex® and Ismatec® pump systems and tubing for transfer, additions, filtration, and more . . 5–29 Syringe pumps offer accurate microflow rates for better R&D results . . . . . . . . . . . . . . . 30–31 Meet filtration pressure demands with gear or piston pumps . . . . . . . . . . . . . . . . . . . 32–36 Get steady, pulseless flow with disposable single-use pump heads . . . . . . . . . . . . . . . Process...

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BioPharma Processing - 7

Masterflex® Tubing Pumps Flow Ranges B/T® Need help selecting? Call the experts! 020-8574-7556 Masterflex® L/S® Digital Miniflex® Pump Systems - Flow range of 0.004 to 315 mL/min (depending on model and tubing size selected) - Tubing calibration function ensures accuracy - Open-head sensor stops drive when pump head is opened - Remote control via 25-pin connector on back of drive - Automatic tubing retention makes tube loading quick and easy Compact, stackable pump with durable ABS housing is easy to wipe down and keep clean. The Miniflex pump head features a wide occlusion angle...

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BioPharma Processing - 8

Masterflex® |Tubing Pumps 10 Flow Ranges P 10.00001 to 3400 mL/min L/S® - Flow rates: 0.06 to 3400 mL/min - Easy up-front control of speed, direction, and start/stop - Reversible motor—purge tubing before or after pumping; ✓ Epoxy resin delivery ✓ Bulk container pump ✓ Coolant/recirculation pump ✓ FDA tablet coating ✓ Adhesive resin delivery ✓ Packaging process pump ✓ Fermentation additions B. Precision washdown modular drive with washdown wall-mount controller Masterflex® L/S® Precision Variable-Speed Modular Pumps pump fluid in either direction - Three-digit LED display shows motor...

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42 LPM Need help selecting? Call the experts! 020-8574-7556 Masterflex® L/S® Variable-Speed Digital ■ Brushless, maintenance-free motor provides ±0.1% speed control accuracy with 6000:1 turndown ratio ■ Bright graphical LCD offers easy programming and four operating modes ■ Ensure dispensing accuracy with antidrip function ■ Get more accurate dispensing with preprogrammed calibration ■ Change based on your needs—drives accept all L/S pump heads for more pumping versatility ■ Programmable, reversible motor accepts up to four pump heads ■ Choose how you want to dispense: volume, copy cycles,...

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BioPharma Processing - 10

Masterflex® |Tubing Pumps 10 Flow Ranges P 10.00001 to 3400 mL/min L/S® applications ✓ Pumping buffer solution ✓ Filling/emptying media bags : ✓ Sterile filtration; sterile fluid transfer ✓ Filtration Masterflex® L/S® Digital Console Process Pumps Transfer, dispense, and meter in lab, process and washdown environments MasterFIex" - IP66 and NEMA 4X rated. Sealed housing and sealed keypad are protected from dust, water, and chemicals in the washdown environment— simply hose down to clean. - Programmable, reversible motor accepts up to two pump heads and offers remote functionality - Flow...

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BioPharma Processing - 11

Need help selecting? Call the experts! 020-8574-7556 Masterflex® L/S® Digital Modular Three dispensing modes and precision low-maintenance motor Dispensing Pumps - Graphical LCD shows four operating modes: continuous run, timed dispense, copy dispense, volume dispense - Antidrip function ensures dispense accuracy - Brushless, maintenance-free motor offers ±0.1% speed control - Remote control capabilities: speed, direction, start/stop/prime, tach output A. Modular Drive with Benchtop Controller - Stackable, splash-resistant ABS plastic controller housing is IP33 rated; drive housing is epoxy...

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