RoboDis_II
20Pages

Your challenge Generate reliable test results within the shortest possible time As a long-standing partner of the pharmaceutical industry we are fully aware of the challenges inherent in the dissolution test procedure. Test results have to be reliable, reproducible and documented fully and comprehensively. At the same time laboratory staff is faced with enormous time constraints, in view of ever shorter production cycles and the need to release batches in increasingly shorter time. Although traditional semi-automatic dissolution testers provide some improvement for these test procedures,...

Who we are ERWEKA – A visionary and experienced partner for the pharmaceutical industry Erweka is one of the leading international manufacturers of premium test equipment for development and quality control of pharmaceutical solid dosage forms. For more than 70 years we have supplied our products to major pharmaceutical and life science companies, development and test laboratories and pharmaceutical-technical universities worldwide. Our vast product portfolio ranges from physical testers to dissolution testers in accordance with USP 1, 2, 3, 4, 5, 6 and 7, and our experience in this sector...

Our innovation - RoboDis II+ RoboDis II+ is our parallel-working, fully automated dissolution tester. All stages of the dissolution processes are computer-controlled and therefore carried out entirely without user intervention. The key element of the fully automatic system is the Disso.NET software developed by ERWEKA, which handles all system functions, including the precise movement of the robot arm, control of the analytic devices, data processing and full documentation. In the standard configuration, RoboDis II+ tests up to 10 batches in accordance with USP methods 1 (Basket) or 2...

Small footprint, great results Laboratory space required to achieve the productivity of a single RoboDis II+ 10-batch system with conventional semi-automatic systems:10+ m Three complete semi-automatic dissolution testers including media preparation and vessel cleaning - this is the amount of floor space you can save with a RoboDis II+ 10-batch system, which has a footprint of no more than 2x1m. Small Footprint, Great Results

RoboDis II+ in R&D Multiple dosage forms RoboDis II+ is capable of handling pharmaceuticals in a variety of different dosage forms. Regardless of whether your laboratory handles tablets, granulates or powders - RoboDis II+ is the ideal, highly flexible and full automated dissolution system for your requirements. As an option even sinkers up to 34 mm are supported. Flexible filtering options There are virtually no limits for filtering with RoboDis II+ the system supports Poroplast inline filters and membrane filters. pH change: half change and optional full change RoboDis II+ provides fully...

Various options for connecting to analytic devices RobDis II+ features fully automated, integrated online analytics, offering a broad spectrum of capabilities ranging from simple spectrophotography with a UV/Vis device to complex HPLC chromatography, or a combination of both. Six media inlets Central to the development were flexible media inlets for rapid test-out of a variety of different formulations – no problem for RoboDis II+ and its integrated media preparation features.

Boost Your Productivity RoboDis II+ for quality control Productivity to suit your requirements with 10, 20 or 40 batches RoboDis II+ productivity can be conveniently scheduled well in advance, independent of staff working hours. Equipped with 40 batches, RoboDis II+ can run, for example through an entire weekend, and have the results ready for evaluation by your laboratory staff on the following weekday. Video recording enables laboratory staff to go back to any desired point of the test for visual inspection and verification. High sample volumes - 40 batches Testing non-stop – there is...

Robotic precision & fault monitoring Each step of the RoboDis II+ test procedure is fully automated and is verified automatically by the software – this means that RoboDis II+ always performs test procedures in exactly the same way, thereby eliminating human errors in simple tasks. RoboDis II+ offers maximum reliability. Space-saving footprint Achieving the productivity of a RoboDis II+ system with other, semi-automatic systems would require four times more space (for a 10-batch system).

RoboDis II+ features Sample magazine for 10, 20 or 40 batches In the 40-batch version, RoboDis II+ enables true 24/7 testing and is capable of handling 40 batches without human intervention. A high-precision robot arm A Festo robot arm takes care of all repetitive tasks within the RoboDis II+ system: Placement and removal of all sample containers and filters, filling with medium, sample withdrawal, basket (dis)mounting, checking of all actions by light barrier and cleaning of the vessels. Integrated controller with Disso.NET Control of all RoboDis II+ functions is provided by an industrial...

40-batch filter magazine The 40-batch option with revolving magazines comes with a 40-batch filter holder. These poroplast filters are mounted and dismounted fully automatically for each test by the robot arm. Built-in media preparation The built-in media preparation feature fully automatically prepares the medium for the testing procedures. Media preparation is configured through the Disso.NET software, with RoboDis II taking care of all other steps. Seven test vessels Precise piston pump Seven USP-compliant test vessels in the RoboDis II+ system support testing in R&E and in quality...

12 Not smarter, but more reliable System Suitability Tests (SST) In each individual process step, RoboDis II+ self-checks by means of integrated System Suitability Tests (SSTs) e.g. filling into each individual vessel volumetrically and testing of each vessel via differential weighing of the MediPrep. Several built-in light barriers validate the steps performed by Robo Dis II+, thus preventing false starts. Not smarter, but more reliable RoboDis II+ performs routine tasks more precisely than any human operator – but without a human operator all its powerful fully automatic features would be...