Esco Pharmacon Downflow Booth, Model DFB-1.5S1-1-C Pharmacon Downflow Booth Introduction Downflow Booths provide containment by utilizing high velocity air to capture airborne dust particles. Downflow Booths are versatile devices that can: • Control exposure risk to hazardous materials for a wide variety of equipment and processes. • Provide Operator Exposure Levels (OEL’s) ≤100 μg/m3 over an 8 hour Time Weighted Average (TWA) when used with good operator techniques. Levels of ≤10 μg/m3 can be achieved by incorporating our High Containment Screen, protecting the operator during sensitive tasks. • Enhance cGMP practices. Basic Principles • Clean (HEPA Filtered) air is supplied from the Downflow Booth Supply Plenum (Booth Ceiling). • ‘Downflow’ of air captures airborne dust particles. • ‘Dirty’ air is pulled to a Low Level Exhaust Plenum (Located at the rear of the booth). • The 'Dirty' air is filtered (F8 fine dust and H13 HEPA filters) to remove entrained dust particulate and is typically re-circulated. • Supply air of unidirectional air from the ceiling plenum at 0.45m/s ± 20% (88.5 FPM ± 20%) when measured at 150mm (5.9") from the ceiling filter or diffuser in the booth • Any potential dust that is generated during handling is suppressed by the downward flow of air and captured by the higher exhaust velocity local to the exhaust grilles. The unique perforated hole pattern ensures a uniform flow of exhaust air into the F8 fine dust filters. • In order to prevent contaminated air leaving the open front of the Booth, a nominal 10% of HEPA filtered air is bled out of the Booth at high level. The same quantity of air enters the Booth through the open face. • Typically with air entrainment systems the region of optimal dust capture decreases exponentially the further you move from the exhaust zone. Due to the design of the Downflow Booth, this effect is minimized resulting in a ‘Containment Zone’ of 1.3 to 1.8 meters (4-6 feet). Features • Modular, easy-to-clean rigid design with minimal joints. • Single, Two Stage or Three Stage HEPA/ULPA filtration can be accommodated. • Removable bulkhead panels enable access to fine dust filter for service from inside the booth. • Re-circulatory Airflow or Single Pass Airflow if solvent or hazardous fumes are present in the process (may also require explosion proof electrics). • Cooling Coils can be fitted to offset heat gains in re-circulatory airflow systems. • HEPA/ULPA gel-seal downflow filters are replaceable from within the booth. Gel-seal is more reliable than conventional gasketed seals. • Voltage-compensating blower(s) ensure stable airflow. • Magnehelic gauges provide convenient and reliable means for monitoring booth airflow and filter condition. • Booths ship supplied in kit form for site assembly. • Compact ceiling and rear plenums maximize usable work area while minimizing floor space. • IQ/OQ protocols available. • Energy-efficient tear-drop light fittings minimize airflow disruption.

Project Process Flow • Milling. • Dispensing. Project Lead Received. Options • Bag-in bag-out filter housings for safe filter change. • Total exhaust airflow. Touch Screen Control Panel (optional) • Built-in cooling coils to offset booth temperature rise. • Comprehensive factory and site acceptance tests include: filter integrity, particle count (air cleanliness), downflow velocity and uniformity, exhaust velocity/ volume, containment zone verification, noise level, light intensity, temperature rise and electrical safety. • Facia cavities for computers, screens, printers. • Containment performance...

DFB-1.5PC-1-C Internal Width Code Body Material Electrical Code Powder Coated * C code only applied if unit is customized Note: The standard internal depth is 2100 mm (82.7"), any different dimension to be regarded as customization. Model DFB, Esco Pharmacon Downflow Booth Technical Specifications Side View Front View Esco Pharmacon Downflow Booth Dimensional Data Model Teardrop lamp Control panel Electrical outlet(s) Side wall Bleed filter Filter plenum H13 HEPA filter Duct Fan house Fan and motor Fine dust filter Rear plenum Airflow (Recirculating Booth) • Clean (HEPA Filtered) air is supplied...

Biological Safety Products Containment / Pharma Products Ductless Fume Hoods / Carbon Filtration General Purpose Scientific Equipment Industrial Lab Equipment In-Vitro Fertilization Products PCR Products Pharmacy Products Lab Animal Research Products Lab Thermostatics Products Lab Ventilation / Chemical Fume Products / Lab Furniture Powder Handling Products Since 1978, Esco has emerged as a leader in the development of controlled environment, laboratory and pharmaceutical equipment solutions. Products sold in more than 100 countries include biological safety cabinets, fume hoods, ductless fume...