ALPHA3 Facility Edition
6Pages

FACILITY EDITION LIGHT SHEET MICROSCOPE U LTRA - THIN LIGHT SHEET M ULTI SAMPLE IMAGING U NRIVALED USER EXPERIENCE

Ultra-thin light sheet microscope Key technologies for best qualitative and quantitative imaging The Alpha3 Facility Edition combines key patented technologies to provide a uniform, optimally resolved and full field light sheet image. The Facility Edition comprises smart dual illuminators coupled with a wide field detection microscope; each multidirectional light sheet illuminator performs real time focus sweeping to extend the thinnest focus area over the entire field of view while improving homogeneity for artefacts‐free imaging. High illumination NA for thinnest optical sectioning Dual...

Automated Multi Scale Imaging Automatic adjustments for any magnification change The Alpha3 Facility Edition is a fully automated system that performs microscope configuration change and auto adjustments when changing objective magnification. 50 µm courtesy of TEFOR, Paris‐Saclay A typical imaging session starts with a quick sample screening using a low mag objective followed by image acquisition at higher magnification objective on a single or multiple regions of interest. Thanks to the access of an extended range of lenses from 2X to 60X, a whole organism or organ can be imaged at a...

Unrivaled user experience with optimized workflow Fast learning curve from sample mounting to image acquisition Easy sample mounting The microscopy system comes with a large range of accessories to accommodate small to large specimen, live or large cleared samples. They provide fast and reproducible mounting while keeping specimen integrity. Automatic sample loading The sample holder is precisely positioned inside the chamber thanks to a magnetic pad. The chamber is then automatically brought in one click in imaging position with a selected dipping lens and its protective cap from corrosive...

LIGHT SHEET SYSTEM Patented dual multi‐directional light sheet generators combined with upright optical microscope Multi‐directional light sheet generators Incl. Laser focus sweeping and Dynamic focusing  Maximum light coverage Motorized illumination objective turret with up to 4 objectives mag / thickness: 2X / 9µm, 5X / 4µm, 10X / 1.5µm, 20X / 1µm*  Image quality (diffraction limited) Laser combiner with up to 6 laser sources from 405nm to 785nm, 50 or 100mW  Very thin light sheet with uniform thickness  Intensity uniformity  Flexible axial resolution  Large choice of excitation...

DETECTION UNIT BX43 upright fluorescence microscope stand with eyepieces, video port, transmitted light (for sample positioning)  Extended range from low to high Detection objectives from 2X to 60X with intermediate magnification changer 2X  Flexibility to meet any application and Air, water, long working distance high NA clearing objectives with correction collar from 1.33 to 1.56  Objectives protected against corrosive Objectives protected with Teflon holders and cover glass, drop protection system  Easy objective cleaning and drop protection Camera Hamamatsu sCMOS Orca Flash or...