Built from Legacy. Driven by Innovation. Born from Olympus’ century of innovation, Evident carries forward a legacy of precision, performance, and trust in scientific imaging. The FLUOVIEW™ FV5000 isn’t just the next confocal—it’s a platform built for every dimension of discovery. From crisp, photon-level quantitation at the surface to deep, multiphoton imaging in thick, living samples, the FV5000 captures biology at every scale. SilVIR™ detectors deliver exceptional sensitivity, 2K resonant and 8K galvo scanning freeze motion in real time, and smart automation enables consistent, reproducible...

Mouse brain slice expressing 7-color Tetbow cleared with SeeDB2 (in utero electroporation). Sample courtesy of: Drs. Satoshi Fujimoto and Takeshi Imai, Graduate School of Medical Sciences, Kyushu University

Absolute Quantitation— Every Pixel, Every Run The new benchmark in advanced microscopy, our SilVIR™ detectors deliver photon-level quantitation with exceptional sensitivity and ultra-high signal-to-noise across the industry’s widest dynamic range. Trust the industry’s first built-in laser power monitor to ensure consistent, reproducible illumination from samples captured today and in the future. Finally, combine beautiful images with beautifully quantifiable results. “The dynamic range of the detectors has allowed us to image a number of different labels that we were not able to previously accomplish...

Expect Exceptional Imaging from Every Level of Signal Clear high and ultra-low signals from the same sample with no compromise in quality. SilVIR™ Next-Generation Detector Technology Built on Evident’s patented silicon photomultiplier design, SilVIR technology captures every photon with exceptional sensitivity and the industry’s widest dynamic range. Low-noise electronics and a built-in laser power monitor maintain illumination stability and ensure reproducible, quantitative results from faint signals to deeptissue imaging. Intensity: 2330 Photon number: 73 Intensity: 48 Photon number: 2 Intensity:...

Speed and Resolution, No Compromises Two Scanners, One Workflow: High-Density Sampling and High-Speed Imaging “The quality of imaging, I’ve never seen something similar before.” Whether you need high-speed series or pixel-dense maps, the FV5000 adapts. Our resonant scanner captures fast cellular dynamics at full clarity across a 20 mm FOV with little to no averaging, giving you high-quality, high-SNR raw images, in up to 438 FPS. Switch to 8K × 8K galvo scanning to image large areas at high spatial resolution with ultra-fast pixel dwell times as short as 0.2 µs. Achieve up to 120 nm XY resolution...

Effortless Super-Resolution Imaging Powerfully Accessible Subcellular Answers Achieve super-resolution imaging on the FV5000 with no additional hardware. By pairing highNA objectives, such as our A Line™ HR series, with FV-OSR software, you can resolve subcellular structures down to 120 nm in XY with ease. FV-OSR automatically adjusts the confocal aperture to capture and enhance high-frequency signal components, producing crisp, detailed images in real time. Combined with the sensitivity of the SilVIR detector, the FV5000 delivers simultaneous super resolution across up to six spectral channels....

• Smart Sample Search quickly locates your sample in XY and Z • Smart Laser Power Adjustment uses AI to optimize signal-to-noise across power setting • Intuitive interface captures complex multidimensional images in just a few clicks • Intelligent Shading Correction automatically creates seamless, high-quality stitched images FLUOVIEW Smart is available with FV5000 inverted configurations. FLUOVIEW Smart is not compatible with gantry, upright, or MPE configurations. AI-powered Smart Sample Search automatically locates your sample in XY and Z in under a minute, reducing manual setup and minimizing...

Smart Simplicity in Action Automated Correction Collar Adjustment The FV5000’s integrated TruResolution™ technology simplifies one of microscopy’s most tedious alignment tasks, objective collar adjustment. In a single click, the system automatically locates the optimal collar position for your sample, eliminating manual trial and error. For thick specimens, TruResolution dynamically fine-tunes the collar during XYZ scans to maintain consistent image sharpness throughout the entire volume. Compatible with many standard objectives, it delivers uniform clarity across diverse samples and imaging...

Reliability and Flexibility, Built to Last The FV5000 is engineered for long-term precision and adaptability, delivering the reliability researchers depend on and the flexibility their science demands. Configure the system for today’s needs and expand effortlessly as your research evolves. Add detectors, cameras, or lasers as workflows advance, or upgrade to multiphoton imaging with the MPE module, enabling single- and multiphoton acquisition as well as second and third harmonic generation. Smart hardware and software continuously monitor and optimize imaging performance, ensuring consistent,...

Built for Reproducibility The FV5000 maintains measurement precision through active system monitoring. The Laser Power Monitor (LPM) ensures consistent laser output across sessions, allowing different users to acquire images under identical conditions, even days or weeks apart. This stability supports the reproducibility required for quantitative and longitudinal studies. To further safeguard performance, the Microscope Performance Monitor (MPM) automatically evaluates system sensitivity and imaging consistency. It detects deviations early, helping researchers maintain confidence in their results...

Software Tools as Dynamic as Your Science Minimize Noise, Maximize Data The FV5000’s software ecosystem adapts as quickly as the biology you study. Advanced AI tools enhance image quality, accelerate analysis, and streamline complex workflows, all without sacrificing scientific rigor. TruAI noise reduction further improves the FV5000’s already high signal-to-noise ratio by using neural networks trained on SilVIR™ detector noise patterns. Whether applied in real time or post-processing, TruAI restores clarity in resonant images and preserves temporal resolution while reducing photodamage. To speed...