accelerate

Product catalog summary

Overview of Accererate® Bone Marrow Concentrate System
The Accererate® Bone Marrow Concentrate System is designed to enhance the concentration of bone marrow cells through a gentle centrifugation process. This system is notable for its single-spin operation, which simplifies the procedure and improves the quality of the concentrate by preserving the fragile buffycoat layer. It is particularly beneficial in surgical settings, offering a quick and convenient method to concentrate cells while minimizing infection risks and enhancing surgical outcomes.

Key Features

High Cell Yield: The system's gentle centrifugal acceleration and deceleration processes ensure a high yield of Bone Marrow Concentrate (BMC) by isolating and preserving the buffycoat layer.
Sterility: The closed system design minimizes contamination risks by requiring only two sterile barrier entries, reducing infection risks significantly.
Flexibility and Convenience: Capable of processing 30-240mL of bone marrow aspirate in a single 12-minute spin, the system is portable and easily transferable between operating rooms.

Scientific Basis and Clinical Potential
Bone marrow concentrate is rich in mesenchymal stem cells, which can differentiate into various tissue types such as bone, tendon, cartilage, and ligament. Concentrating these cells through centrifugation reduces the volume needed for injection while maintaining a high concentration of cells, potentially enhancing bone repair and regeneration in orthopedic surgeries.

Performance and Efficacy

Cell Concentration: Testing indicates a 400% increase in total nucleated cell concentration and a four-fold increase in colony-formation units of fibroblasts (CFU-F) compared to baseline bone marrow aspirate (BMA).

Limitations
The Accererate Concentrating System has not been evaluated by the FDA for specific therapeutic indications.

Conclusion
The Accererate® Bone Marrow Concentrate System offers a significant advancement in the concentration of bone marrow cells, providing high yields and maintaining sterility, which are crucial for improving surgical outcomes and reducing infection risks.

Catalog excerpts

bone marrow concentratE system the science of accelerated healing

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Delivering the Science of Accelerated Healing. Accererate® Bone Marrow Concentrate System is improving the way bone marrow is concentrated by offering high-quality cell yields through gentle centrifugation, which preserves the fragile buffycoat layer. The system sets itself apart by providing single-spin operation, reducing processing steps and improving concentrate outcomes. This easy-to-use system provides a fast and convenient method for concentrating cells in the operating room, while reducing a patient’s risk of infection and improving surgical outcomes. Accererate® Delivers High Bone Marrow...

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Maximizing Bone Marrow Cell Concentration6 Testing performed by BioScience Research Associates, Inc., an affiliate of Harvard Medical School, demonstrates that BMC processed by the Accererate system provides a 400 percent increase in total nucleated cell concentration compared to the baseline of bone marrow.6 Compared to the baseline of BMA, BMC demonstrates a four-fold increase in the colony-formation units of fibroblasts (CFU-F). Total Nucleated Cells (Average of 20 patients) CFU-F (Average of 20 patients) 3500 3000 Total Nucleated Cells (106/mL) References 1. Henigou P, Poignard A, Beaujean...

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