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Calcium Phosphate Cement

Calcium Phosphate Cement

Calcium Phosphate Cement

Product catalog summary
Overview: Ossilix is a next-generation calcium phosphate cement designed for filling bony defects in cancellous bone. It addresses the limitations of first-generation cements by offering improved tensile strength, flexural strength, and fracture toughness, along with better handling properties.
Advantages:
  • Biocompatible and supports natural bone remodeling.
  • Higher compressive strength than cancellous bone.
  • Easy mixing and delivery system.
  • Fast setting time of approximately 6 minutes at 37°C.
  • Drillable and compatible with surgical hardware.
  • Can be used as an autograft extender.
Clinical Applications:
  • Filling simple voids in metaphyseal bone due to tumors, cysts, or defects.
  • Traumatic fractures in areas such as the distal radius, proximal humerus, pelvic bone, proximal femur, distal femur, tibial plateau, tibial pilon, and calcaneus.
  • Osteotomies and oncological applications.
  • Revision of total joints and iliac crest backfill.
Composition and Science: Ossilix is composed of a calcium phosphate starting powder reacted with diluted silicate liquid, forming low crystalline hydroxyapatite. This creates an osteoconductive scaffold that supports bone remodeling.
Histology: Studies show Ossilix is highly biocompatible and osteoconductive, with extensive bone apposition and no adverse tissue reactions observed in vivo.
Biomechanical Analysis: In vivo studies demonstrate that Ossilix maintains strength above cancellous bone during remodeling, visible under fluoroscopy for proper placement.
Indications & Case Studies: Ossilix is used in various trauma cases such as tibial plateau fractures, distal radius fractures, and calcaneus fractures. It is also applied in oncology for filling bone voids and in total joint revisions.
Ordering Information: Ossilix is available in different forms and sizes, including Ossilix Form and Ossilix Fil, with catalog numbers provided for ordering.
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Catalog excerpts

Calcium Phosphate Cement-1

Surgeon focused. Patient driven.™

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Calcium Phosphate Cement-2

Ossilix is a high performance next generation calcium phosphate cement indicated for filling bony defects in cancellous bone. This material was designed to overcome the limitations of the first generation calcium phosphate cements. First generation cements had good compression strength but were weak in tension, flexural strength and fracture toughness, which combined with poor handling properties, have limited their use in fracture fixation. ' Advantages • Biocompatible • Allows for natural bone remodeling, or healing, while still maintaining the strength above that of cancellous bone - Immediate...

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Calcium Phosphate Cement-3

Remodeling Case Study DRILLABLE OSTEOCONDUCTIVE SCAFFOLD Composition Biomechanical Analysis Bone remodeling is the healing process whereby old bone is naturally removed A clinically relevant understanding of long-term strength of and replaced with new bone. Ossilix is similar in composition to the mineral defects treated with calcium phosphate bone void fillers (or any other bioactive material) are appropriately evaluated only in vivo. An in vivo biomechanical study was performed at four A calcium phosphate starting powder is reacted with diluted silicate liquid, weeks and six months post-implantation...

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Calcium Phosphate Cement-4

Indications & Case Studies Total Joint Revision TRAUMA Tibial Plateau Fracture view shows extensive osteolysis in both compartments of tibial bone underneath the tibial tray. CT shows low energy Tibial Plateau fracture view of filling the bony voids with Ossilix. view of Ossilix implant and new total knee joint has been inserted. X-ray shows the fixation by plating and Ossilix implantation Distal Radius Fracture X-ray showing on extra-articular fracture. Lateral view shows Ossilix implantation in both dorsal and volarside of distal radius. Shoulder riding high compromised glenoid 10cc Ossilix...

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Calcium Phosphate Cement-5

1. Lin, J., et al. Improved Flexural Strength of a Novel Craniomaxillofacial Cement. Orthopaedic Research Society Transactions Vol.30, Washington, D.C., 2005. 2. Banki, P, et al. Optimization of the Osteoinductiveness and Mechanical Properties of Calcium Phosphate Bone Cement using Demineralized Bone Matrix. Orthopaedic Research Society Transactions Vol.29, San Francisco, California, 2004. 3. Yetkinler, D N., et al. In Vitro and In Vivo Evaluation of Two Calcium Phosphate Cements. Orthopaedic Research Society Transactions Vol.29, San Francisco, California, 2004. 4. Lin, J., et al. Increased Fracture...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.