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PHARMX® HIGH SHEAR GRANULATOR

PHARMX® HIGH SHEAR GRANULATOR

PHARMX® HIGH SHEAR GRANULATOR

Product catalog summary
Overview: The PHARMX® High Shear Granulator is designed for efficient mixing and granulation, optimized for various pharmaceutical processes including R&D, pilot, and production applications. It offers design flexibility to ensure peak performance and can be customized to meet specific processing challenges.
Benefits: The granulator simplifies scale-up, minimizes process downtime, optimizes production, reduces maintenance, and improves product quality.
High-Shear Granulation Process: This process involves turning powders into dense granules suitable for tableting or coating. The powders are mixed in a sealed bowl with a rotating impeller, and liquid is added to form granules. A high-speed chopper shears the granules and removes air, continuing until the desired size and density are achieved. The product can be dried in the bowl or transferred to a fluid bed dryer.
System Features: The PHARMX® granulator features a bottom-driven mixing impeller and side-mounted chopper, with bowl geometry optimized for 30-90% capacity. The dome-shaped lid ensures efficient mixing, and the system includes auto-cleaning and liftable tool systems for easy maintenance and reduced downtime.
Advantages: The system supports flexible bowl configurations, homogeneous mixing, and precise liquid addition. It is equipped with robust variable speed chopper and impeller drive systems for maximum energy transfer and consistent impeller tip speed for all models.
Control Software: The Batch Architect™ process control software maximizes operating flexibility, suitable for both R&D and FDA-compliant applications. It supports manual or recipe-based control and runs on Allen-Bradley® Logix processors.
Specifications: The document provides detailed specifications for various models, including total bowl volume, impeller speed range, and power requirements. The models range from PX1 to PX1250, with varying capacities and power configurations.
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Catalog excerpts

PHARMX® HIGH SHEAR GRANULATOR-1

PHARMX® HIGH SHEAR GRANULATOR EFFICIENT MIXING AND GRANULATION OPTIMIZED TO YOUR PROCESS

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PHARMX® HIGH SHEAR GRANULATOR-2

MAXIMIZE YOUR BATCH DESIGN FLEXIBILITY ENSURES PEAK PERFORMANCE FOR HIGH SHEAR GRANULATING MIXERS Whether you need solid dosage technology for R&D, pilot or production applications, Fluid Air can help. Our PHARMX® high-shear granulating mixer can be quickly and cost-effectively customized to meet your unique processing challenges. Processing ingredients with special requirements? One pot processing? Let us help you optimize your production. BENEFITS: • implify your scale-up S • inimize process downtime M • Optimize production • educe maintenance R • mprove product quality I What is High-Shear...

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PHARMX® HIGH SHEAR GRANULATOR-3

EFFICIENT GRANULATING AT UP TO 90% BOWL CAPACITY Mixing Impeller System PROCESSING POWDERS, GRANULES, AND LIQUIDS TO REQUIRED SPECIFICATIONS The PHARMX® high-shear granulator has a mixing bowl with a bottom-driven mixing impeller and side mounted chopper. The bowl geometry is optimized to permit working volumes from 30-90% of full capacity. EFFICIENT, HOMOGENEOUS MIXING EVEN AT LARGER CAPACITIES CREATING A QUALITY PRODUCT The dome shaped lid permits product to perform a complete roll over as it moves up the side of the vessel wall. This ensures efficient mixing even when running at larger operating...

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PHARMX® HIGH SHEAR GRANULATOR-4

EASY TO USE BATCH ARCHITECT TM PROCESS CONTROL SOFTWARE MAXIMIZES OPERATING FLEXIBILITY • imple enough for R&D scale machines; sophisticated enough S for applications requiring 21 CFR Part 11 FDA compliance • onfigure for manual control or optional phase or recipe-based C control • Runs on Allen-Bradley® Logix processors, RSLogixTM 5000 Software, PanelView PlusTM or FactoryTalk® SE Platform Batch Architect ProTM Status Screen Allen-Bradley is a trademark of Rockwell Automation PHARMX® HIGH-SHEAR GRANULATING MIXER SYSTEMS: SPECIFICATIONS Model Number Total bowl volume (L) Charge- max. liters @...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.