C1
C1
The C1 System is an innovative solution for single-cell genomic analysis, offering precision, ease of use, speed, and flexibility. It allows researchers to measure gene expression profiles with single-cell accuracy, providing a comprehensive and automated workflow that minimizes technical errors and enhances reproducibility.
- Single-cell Precision: Enables accurate measurement of gene expression differences.
- Ease of Use: Simplified cell isolation and preparation with an intuitive interface.
- Speed: Provides data in less than a day from cell input.
- Comprehensive Workflow: Automated processes ensure reliable results.
- Flexibility: Expandable for whole transcriptome and variant discovery.
The C1 System utilizes Fluidigm's microfluidic technology to isolate, process, and profile individual cells. This approach reduces variability and technical noise, allowing for detailed studies of cell differentiation, disease biomarkers, RNAi knockdown validation, and drug screening.
- C1 Instrument: Automates isolation, lysis, and preamplification of single cells.
- C1 IFC: Integrated fluidics circuit for capturing and preparing 96 individual cells.
- C1 Reagent Kit: Ready-to-use kit for cell suspension, lysis, and purification.
- Capture Cells: Load cells in a single step and separate them into individual chambers.
- Verify: Quality control to verify captured cells and distinguish live from dead cells.
- Lyse: Rapid cell lysis method without RNA purification.
- Reverse Transcribe and Preamplify: cDNA synthesis and target amplification occur on the same sample.
- Harvest: Preamplified products are pooled and transferred for quantitative PCR analysis.
The C1 System offers a streamlined, automated solution for single-cell genomic analysis, enhancing productivity and accuracy in gene expression studies. It is designed for research use only and not for diagnostic procedures.
Catalog excerpts
EVERY CELL IS UNIQUE THE C1 SYSTEM: DEFY THE LAW OF AVERAGES • Single-cell precision—greater accuracy to measure differences in gene expression profiles • Easy to use—simplified cell isolation and preparation with a streamlined workflow and intuitive interface • Fast—cell input-to-data in less than a day • All in one—comprehensive, automated workflow generates reproducible and reliable results • Flexible—expandable into whole transcriptome and variant discovery Individual cells vary as much as the researchers who study them. Traditional methods of extraction, isolation by pipette, and processing...
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C1 Components The C1 system is the world’s first commercially available, automated single-cell isolation and preparation system for genomic analysis. The C1 System provides an easy and highly reproducible gene expression workflow to process 96 single cells across 96 mRNA targets. In this format, our single-cell workflow enables you to measure the expression of hundreds of genes in just a few hours compared to experiments that would normally take days using traditional systems. With this new system you can rapidly explore unique attributes of individual cells without the technical variability...
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CORPORATE HEADQUARTERS 7000 Shoreline Court, Suite 100 South San Francisco, CA 94080 USA Toll-free: 866 359 4354 | Fax: 650 871 7152 fluidigm.com ©2014 Fluidigm Corporation. All rights reserved. Fluidigm, the Fluidigm logo, BioMark, and C1 are trademarks or registered trademarks of Fluidigm Corporation in the U.S. and/or other countries. All other trademarks are the property of their respective owners. PN 100-5477 C1 For Research Use Only. Not for use in diagnostic procedures.
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