Clinical & Laboratory Evidence

CONTENTS Laboratory Micro-Efficacy Testing Proven against more than 30 HCAI-causing pathogens in 5 minutes at 8 feet. (Microchem Laboratories. 1304 W. Industrial Blvd. Round Rock, Texas 78681. USA.) 4 log reduction against a range of multi-drug resistant bacteria and spores in both clean and dirty conditions. (Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.) Clinical Evidence Cardiff University – Jean Yves Maillard, MD The Violet by Clinell Room Sanitiser produces a >4 log reduction against a range of multi-drug resistant...

HOW ULTRAVIOLET LIGHT WORKS Violet by Clinell Room Sanitiser uses germicidal wavelength ultraviolet radiation (UV-C) to kill microorganisms. How it works The sun emits three types of UV radiation: UV-A (315nm-400nm): Black light used for tanning lamps, can be harmful to eyes. UV-B (280nm-315nm): Can cause sunburn and skin cancer. UV-C (200nm-280nm): Kills microorganisms via short-wavelength ultraviolet radiation. This radiation is normally stopped by the Earth’s ozone layer. Ozone layer The power of UV-C The Violet by Clinell Room Sanitiser generates artificial UV-C energy by ionizing low pressure...

Room decontamination units (such as ultraviolet-C and hydrogen peroxide systems) aid in reducing environmental contamination after terminal room cleaning and disinfection2. Third-party testing results for the Violet by Clinell Room Sanitiser against C. difficile spores and MRSA Clostridium difficile (endospores) Methicillin Resistant Staphylococcus aureus (MRSA) Distance (feet) Time (mins) % Reduction compared to control Safe and effective way to reduce or eliminate microorganisms3 Log reduction compared to control Advantages over other no-touch room decontamination technologies R apid room decontamination....

PERFORMANCE VALIDATED BY THIRD-PARTY LABORATORY MICRO-EFFICACY TESTING Kills more than 30 HCAI-causing pathogens in 5 minutes at 8 feet. - 4 log reduction of Clostridium difficile spores - reater than 5 log reduction of over 20 pathogens including G MRSA, VRE and CRE. Testing Distance and Time: 8 feet, 5 minutes 4 Log Reduction Fungi • Candida albicans Bacterial Spores • Clostridium difficile • Adenovirus • Hepatitis A Virus • Hepatitis C Virus† • Herpes Simplex Virus 2 • Human Coronavirus • Respiratory Syncytial Virus • Rhinovirus • Rotavirus • Enterovirus 68 • Herpes Simplex Virus 1 • Influenza...

CARDIFF UNIVERSITY The Violet by Clinell Room Sanitiser produces a >4 log reduction against a range of multi-drug resistant bacteria and spores, in both clean and dirty conditions. Principal Investigator: Jean Yves Maillard, MD, Professor of Pharmaceutical Microbiology, Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, United Kingdom. Test the bactericidal and sporicidal efficacy of the Violet by Clinell Room Sanitiser against laboratory strains and clinical isolates of a range of MDROs in both clean and dirty conditions. These include C. difficile, MRSA, VRE,...

ST. MARY’S HOSPITAL FOR CHILDREN Violet by Clinell Room Sanitiser reduced viral infection incidence by 44% among pediatric patients in a long-term care facility when used as an adjunct to standard cleaning protocols. Principal Investigator: Marianne Pavia, MS, BS, CIC, FAPIC, St. Mary’s Hospital for Children, Bayside, NY. To examine the effect of the Violet by Clinell Room Sanitiser efficacy on viral pathogen infection incidence among pediatric patients at St. Mary’s Children’s Hospital, Bayside. NY. The Violet by Clinell Room Sanitiser was deployed for a 12-month period – a single device was...

The Violet by Clinell Room Sanitiser reduced C. difficile infection (CDI) rates by 25% and averted an estimated $348,528–$1,537,000 in annual direct medical costs in Hematology/Oncology units. Principal Investigator: David Pegues, MD, Professor of Medicine, Hospital of the University of Pennsylvania To examine the impact of Violet by Clinell Room Sanitiser deployment combined with manual surface disinfection with bleach on C. difficile infection rates in Hematology/Oncology units over a 12-month evaluation period. The Violet by Clinell Room Sanitiser was deployed for a 12-month intervention period,...

JOHNS HOPKINS HOSPITAL The Violet by Clinell Room Sanitiser achieved a >5 log reduction against carbapenem-resistant Enterobacteriaceae (CRE; K. pneumoniae, E. coli, and E. cloacae) in patient rooms. Principal Investigator: Lisa Maragakis, MD, MPH, Senior Director of Infection Prevention and Associate Professor of Medicine, The Johns Hopkins Health System To examine Violet by Clinell Room Sanitiser efficacy against carbapenem-resistant Enterobacteriaceae (CRE; K. pneumoniae, E. coli and E. cloacae) plated on Formica®. This study is part of a cluster, randomised, two-period crossover trial focused...

CLEVELAND CLINIC The Violet by Clinell Room Sanitiser effectively reduced the presence of multidrug-resistant organisms (MDROs), including C. difficile and methicillin-resistant Staphylococcus aureus (MRSA) in patient rooms. Principal Investigators: Abhishek Deshpande, MD, PhD, Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University. To examine Violet by Clinell Room Sanitiser effectiveness against nosocomial pathogens in hospital rooms, including C. difficile and methicillin-resistant Staphylococcus aureus (MRSA). This study is part of...

LOUIS STOKES CLEVELAND VA MEDICAL CENTRE The Violet by Clinell Room Sanitiser effectively kills C. difficile and methicillin-resistant Staphylococcus aureus (MRSA); standardised UV-C device efficacy testing is needed so that different devices can be compared. Principal Investigators: Curtis Donskey, MD, Professor of Medicine, Case Western Reserve University and Staff Physician, Infectious Diseases Section, Louis Stokes Cleveland VA Medical Centre To determine the impact of variation in UV-C efficacy test methods on log reduction results. Two UV-C devices, including the Violet by Clinell Room...