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New generation Size Exclusion Chromatography (SEC) columns

New generation Size Exclusion Chromatography (SEC) columns
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New generation Size Exclusion Chromatography (SEC) columns - 1

New generation Size Exclusion Chromatography (SEC) columns Maximized resolution and optimized run time for small-scale preparative purification and analysis Our new generation size exclusion chromatography columns called “Increase” are designed for high resolution in small-scale preparative purification and analysis for sample volumes up to 500 µL. They deliver improved performance compared to predecessor columns*: • Reduced run time with maintained resolution for time saving or increased throughput • Higher resolution for improved protein purity and analysis data • Higher lot-to-lot consistency for better reproducibility In 2017, GE expands the range of new generation SEC columns with Superdex™ 30 Increase • Four choices of new generation SEC resins for small-scale preparative purification and analysis • Superdex 30 Increase is the replacement for Superdex Peptide columns Peptides and other small biomolecules Fractionation range Mr ~ 100 to 7000 Recombinant tagged proteins Fractionation range Mr ~ 3000 to 70 000 mAb and other antibodies Fractionation range Mr ~ 10 000 to 600 000 Larger proteins and protein complexes† Fractionation ra

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New generation Size Exclusion Chromatography (SEC) columns - 2

New generation SEC columns deliver improved performance compared to predecessor columns* The agarose resins have been optimized to deliver improved performance compared with their predecessors (smaller and more rigid beads, narrower particle size distribution, higher selectivity). Higher resolution at the same flow rate 800 Flow rate: 0.5 mL/min 0.5 mL/min Flow rate: Superdex™ Peptide 10/300 GL 10/300 400 Superdex™ Peptide GL Superdex 30 Superdex10/300 GL 10/300 GL Increase 30 Increase 350 Superdex Superdex 250 Peptide 30 Increase 10 20 20 30 30 40 Retention time (min) time (min) Retention...

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