consigma-coater-2018-170309

consigma-coater-2018-170309

consigma-coater-2018-170309

Product catalog summary
Introduction
The ConsiGma™ Coater by GEA is a cutting-edge tablet coating technology designed to enhance continuous manufacturing (CM) processes in the pharmaceutical industry. It offers a revolutionary approach to tablet coating, providing increased yields, reduced costs, and improved production flexibility.

Specifications and Features
The ConsiGma™ Coater is engineered to handle small quantities of tablets at high rates, ensuring precise and uniform coating even for hygroscopic or friable tablets. It utilizes a cascading movement for tablets, allowing for higher fluid application rates and improved coating uniformity compared to traditional methods. Key features include:
  • Continuous coating capability at 30 kg/h
  • Short processing time with a target weight gain of 3% in less than 10 minutes
  • Modular design suitable for R&D with a minimum batch size of 1.5 kg
  • Low humidity process ideal for moisture-sensitive materials
  • High accuracy with a relative standard deviation (RSD) of less than 1%


Benefits
The technology offers significant advantages over conventional systems, including:
  • Improved coating uniformity and thickness
  • Reduced processing time and material usage
  • Lower attrition rates and gentle handling of tablets
  • Cost savings in terms of time, materials, and process revalidation
  • Compact design requiring less technical space and cleaning


Applications
The ConsiGma™ Coater is suitable for a variety of pharmaceutical applications, including the coating of difficult-to-coat shapes, friable tablets, and multilayer coatings. It supports the industry's shift towards continuous processing to meet stringent regulatory standards and improve production quality.

Conclusion
GEA's ConsiGma™ Coater represents a significant advancement in tablet coating technology, offering a flexible, efficient, and cost-effective solution for modern pharmaceutical manufacturing needs.
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Catalog excerpts

consigma-coater-2018-170309-1

ConsiGma™ Coater Revolutionary, high performance tablet coating technology

 Open the catalog to page 1
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ConsiGma™ Coater An Enabling Technology Another leap forward for continuous manufacturing GEA has been pioneering continuous manufacturing (CM) Introducing a paradigm shift in tablet coating, this new solutions for several years and helping customers to develop, type of coater entrains tablets in a cascading movement that evaluate and optimize continuous processing techniques to enables greater fluid application rates (higher coating build- enable them to bring new products to market faster and cheaper. rates) than traditional coating pans. The functionality of enteric coatings, for example,...

 Open the catalog to page 2
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Features and Benefits Cascade dynamics and spray/substrate interaction offer improved coating uniformity Incorporating a small, simple and modular design, a batch of tablets from as little as 1.5 kg is, under the influence of radial air knives, induced using a centrifugal process to form a stable, gravity free cascade inside a perforated wheel rotating at high speed. Increased drying efficiency is achieved by spraying the coating suspension into a cascading cloud of tablets. As such, the process is much faster, offering a target weight gain of 3% (15% solids content) in less than 10 minutes —...

 Open the catalog to page 3
consigma-coater-2018-170309-4

Compact, Precise and Flexible Faster processing times enable highly accurate coating PAT-compatible, the ConsiGma™ coater is easy to clean and offers significant cost savings compared with conventional systems in terms of time, materials, downtime, process revalidation, stability testing, etc. With a smaller technical space requirement than established technologies, less cleaning and a reduced plant area is needed. And, being a continuous production technology, no scaleup is required and the maximum batch size is almost infinite. The pharmaceutical industry is looking at continuous processing...

 Open the catalog to page 4
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.