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Glubran 2 ENDOVASCULAR

Glubran 2 ENDOVASCULAR

Glubran 2 ENDOVASCULAR

Product catalog summary
Overview: This document analyzes an endovascular embolization agent, emphasizing its dual role as an embolizing and sclerotizing agent. It is noted for its high haemostatic power and ease of preparation, making it ideal for emergencies.
Specifications: The agent is compatible with standard 4F catheters and effective in patients on anticoagulants. It is CE authorized for endovascular use, creating a permanent occlusion. The product is transparent, with a cyanoacrylate odor and water-like density, free from toxic solvents and pain-inducing properties.
Key Properties: The agent functions as an adhesive, sealant, haemostatic, bacteriostatic, sclerosing, and liquid embolizing agent. It polymerizes at 45°C, lower than typical cyanoacrylates, without causing tissue necrosis. It has high tensile strength and forms a thin, sealing, waterproof film.
Applications: It is used in arterial and venous bleeding, AVM, fistulas, varicocele, cysts, tumors, and portal vein embolization. It is effective in wet environments and inhibits bacterial growth for about 7 days.
Procedural Guidelines: The document details procedures including angiographic examination, catheterization, hemodynamic evaluation, and injection techniques. It stresses mixing the agent with Lipiodol to delay polymerization and improve radiopacity.
Recommendations: It advises against using the agent with polycarbonate or silicone materials and provides storage and handling guidelines. It also emphasizes using appropriate syringes and stopcocks.
Conclusion: The embolization agent is a versatile, cost-effective solution for various medical conditions, with high success rates and minimal complications.
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Catalog excerpts

Glubran 2 ENDOVASCULAR-1

Building the perfect Embolization

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Glubran 2 ENDOVASCULAR-2

Great penetration capacity also suitable for distal and very peripheral targets 68,71,77,79,81,82 It does not cause pain 20,27,85 It does not contain toxic solvents 86 Effective and quick 1,20,38,48,57 Easy to prepare 8,20,23,31,48 Suitable for emergencies 38,57,58 High haemostatic power 3,7,8,48,57,76 Can be used in combination with other embolizing agents (Spirals and Microspheres) 38,48,75,79 Reduced costs: “This treatment is safe, effective and a “low cost” treatment with a high success rate” 1,20 Effective even in patients on anticoagulants or affected by inherited coagulation disorders...

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Glubran 2 ENDOVASCULAR-3

SIX PRODUCTS IN A DROP. ADHESIVE High tensile strength. Acceptable minimum load is ≥ 435 N [approx. 18 Kgf/cm2].2-3 Applied with dedicated nebulizing devices it forms a thin film with sealing and waterproof properties due to its synthetic nature and strong adhesive power.3-6 Blocks bacterial growth for an average of 7 days.10-12 Injected into the lumen of a vessel/varices, polymerize generating a plastic cap causing thrombosis and subsequent fibrosis and sclerosis.13-17 Injected into a blood vessel polymerizes building a cast adhers to the vessel occluding it such as an embolus. It causes completely...

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Glubran 2 ENDOVASCULAR-4

INTERVENTIONAL RADIOLOGY PRE POST EMBOLIZATION ARTERIAL EMBOLIZATION FOR BONE TUMOURS 31

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Glubran 2 ENDOVASCULAR-5

HEAD & NECK AVM HEMORRHAGE IN A YOUNG PATIENT 62 After Glubran®2 injection the AVM was completely obliterated.

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Glubran 2 ENDOVASCULAR-6

GUIDELINES FOR USING 1. Careful preliminary angiographic examination 2. Selective and superselective catheterisation of the area to be embolised Identification of the afferent and collateral vessels and any eventual AV fistulas, with oblique and cranio-caudal projections 3. Careful hemodynamic evaluation 4. Dilute with Lipiodol®: a) To delay the Glubran®2 to polymerisation start time b) To make it radiopaque 5. Mix the two compounds uniformly Immediately before injection (with a 3-way resistant stopcock or in a steel bowl) Polymerisation start 6. Wash the catheter with glucose or dextrose solution...

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Glubran 2 ENDOVASCULAR-7

Jan-Feb;31(1):196-200. 43. Heye S, Maleux G, Wilms G. Pain experience during internal spermatic vein embolization for varicocele: comparison of two cyanoacrylate glues. Eur Radiol. 2006 Jan;16(1):132-6. 44. Gandini R, Spinelli A, Konda D, Reale CA, Fabiano S, Pipitone V, Simonetti G. Superselective embolization in posttraumatic priapism with Glubran 2 acrylic glue. Cardiovasc Intervent Radiol. 2004 Sep-Oct;27(5):544-8. 45. Schoder M, Cartes-Zumelzu F, Grabenwöger M, Cejna M, Funovics M, Krenn CG, Hutschala D, Wolf F, Thurnher S, Kretschmer G, Lammer J. Elective endovascular stent-graft repair...

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