One drop, to unify.GEM SOLUTION COMES FROM EVOLUTION.

EFFECTIVE 1-13 • Rapid wound closure (60-90 sec”) 1-8 • Excellent aesthetic results 2-6,9,10 • Infection risk prevention 2,3,8,10-12 • Trauma 2,10,11,13 and inflammation 7,11 reduction COMFORTABLE 2-41013 • Painless2'7,11,15 • Transparent and water resistant 5'10'15 EASY 1,2,5,10,11,15 • Ready to use • Easy to apply PRECISE 14 • Product fluidity, • Ergonimic bottle, • Dedicated tip, allow for a controlled application even in areas that are difficult to treat14 especially for closing wounds on the face and the neck or where the application is difficult (e.g. curved areas, such as elbow, knee,...

NBCA OCA (N-BUTYL-2 CYANOACRYLATE) (2-OCTYL CYANOACRYLATE) The two monomers (NBCA+OCA) ensure: > Elasticity 8,10 > No polymerisation in the presence of air 14 > Polymerisation temperature of 45 °C, much lower than monomeric skin adhesives 14 I_I_I_I_I_I_I_I_I

Treatment of lacerations, wounds and skin injuries on the face, limbs and torso caused by trauma or surgical incisions.

TREATMENT OF LACERATIONS, INCISIONS AND SKIN LESIONS Emergency Room SKIN LESIONS CAUSED BY TRAUMA AND CUTS Trauma laceration Operating Room IATROGENIC WOUNDS C-Section Cutting in Thyroid Surgery Trocar insertion

Certified Quality. Glubran® Tiss 2 has obtained the CE Product Certification in 2007 from the 0373 Notified Body – Istituto Superiore di Sanità Quality Certifications from the TUV (Italian Health Institute). SUD Certification Body: EN ISO 13485:2016 UNI EN ISO 9001:2015 Medical Device Single Audit Program (MDSAP) Bibliography 1. Lombardi CP, Bracaglia R, Revelli L, Insalaco C, Pennestrì F, Bellantone R, Raffaelli M. Aesthetic result of thyroidectomy: evaluation of different kinds of skin suture. Ann Ital Chir. 2011 Nov-Dec;82(6):449-55 2. Gulalp B, Seyhan T, Gursoy S, Altinors MN. Emergency wounds...

A range of solutions in continuous evolution. 10 sterile single doses in aluminium blister packs - 2 year validity

SOLUTION COMES FROM EVOLUTION. GEM Via dei Campi 2 - PO Box 427 - 55049 Viareggio (LU) Italy Tel. +39 0584 389784/391388 - Fax +39 0584 397904 www.gemitaly.it - [email protected]