Human Papillomavirus NeoPlex™ HPV29 Detection NeoPlex™ HPV HR Innovative High-Level Multiplex Real-time PCR for Your Advantage NeoPlex™ HPV Assay Introduction Human papillomavirus (HPV) infection is recognized as one of the leading causes of infection-related cancers in both men and women. Currently, more than 200 types of HPV are known, and high-risk HPV is the main cause of various cancers of the cervical, vulva, vagina, penis, anus, head and neck. Other HPV types, including low-risk HPV, also cause genital warts and various cancers. In fact, because the prevalence of other HPV types constantly increases and duration of multiple HPV infections continues, the possibility of the risk of developing cancer in various body parts is considered significant. Therefore, individual identification of HPV types with a broad spectrum has become more important. Simultaneous multiplex testing for the most HPV 29 genotypes Fastest TAT Quick test results within short analysis time of 2.5 hours TAT Superior Performence NeoPlex™ HPV assay is a high-level multiplex real-time PCR kit that can simultaneously detect and identify HPV high-risk and up to 29 HPV maximum genotypes, based on Genematrix’s proprietary C-Tag™ technology. High sensitivity and specificity based on C-Tag™ technology Maximum Targets Minimum Tubes Full Genotyping and Screening Key Features · Single-tube multiplex real-time PCR assay · Advanced sensitivity and specificity · Maximum genotyping with superior clinical performance · The latest IARC HPV classification applied : HPV67 and HPV70 Included · Fast turnaround time (TAT) · User-friendly workflow · Whole process monitoring with endogenous internal control · UDG System to prevent carry-over contamination Maximum Targets Specimens · Liquid based cytology (LBC) Compatible Instrument · Real-time PCR: CFX96™ Dx System (Bio-Rad) CFX Opus 96 Dx Real-Time PCR System (Bio-Rad) · Automatic nucle

C-Tag™ technology C-Tag™ technology overcomes the limitations of conventional real-time PCR by analyzing multiple pathogens simultaneously. Because TaqMan assay can analyze only one target in one channel, multiplexing of fluorescence channels cannot be implemented. To compensate for these shortcomings, C-Tag™ technology employs target-specific tagging primers to enable multiple analysis of 1 up to four targets in a single fluorescence channel. Patent No. KR10-1961642, US11,193,161 Clinical Performance The excellent clinical performance of the NeoPlex™ HPV29 and HR is demonstrated with the 1,986...

Why is comprehensive genotyping important? 01. Various Diseases and Effects of Vaccination Different types of human papillomavirus (HPV) cause cancers of the vulva, vagina, cervix, penis, anus, and the back of the mouth and upper part of the throat (oropharynx)1 , and persistent infection with HPV is known to progress from cervical dysplasia to cancer. Therefore, genotyping analysis allows early detection of HPV in the early stage of cervical dysplasia to prepare for the risk of cancer development. Furthermore, despite the HPV vaccination rate expanding rapidly, the prevalence of other genotypes...