mi ENeoPlex^^B Innovative Multiplex Real-Time PCR Assay NeoPlex™ Respiratory Bacteria Panel Simultaneous Detection of 8 Respiratory Bacteria • Streptococcus pneumoniae (SP) Single-Tube Multiplex PCR Test One-Step Real-Time PCR Automation Support • Single-Tube Real-Time PCR Reaction By Genematrix’s Proprietary C-TagTM Technology • High Inclusivity Identifies 8 major bacteria that cause acute lower respiratory tract infections Also dectects M. catarrhalis, a common cause of pneumonia associated with COPD* B. parapertussis is also detectable which cannot be prevented by Pertussis vaccine *COPD: Chronic obstructive pulmonary disease • Superior Clinical Performance LOD : < 10-50 copies/rxn Clinical Sensitivity: 98.4% - 100% Clinical Specificity: 99.7% - 100% • Ease of Use Automated analysis with Neoplex™ Viewer software One-Step RT-PCR without separate cDNA synthesis step Fast Turnaround Time (TAT) Within 4 hour from nucleic acid extraction to result analysis, enabling same-day report

Workflow C-TagTM Multiplex Real-Time PCR Step 1 (1 hr) Data Analysis Manual or Automatic Extraction NeoPlex™ Viewer Simultaneous Detection of 8 Bacterial Respiratory Pathogens in a Single PCR Test Fast Turnaround: Less than 4 Hour of Analysis and Same-Day Report Compatible Instruments Compatible with Automatic Nucleic Acid extraction euipment CFX96 Real-Time PCR System (Bio-Rad) Specimens Nasopharyngeal swab Sputum Series Products NeoPlex NeoPlex NeoPlex RV-Panel A : Flu A, Flu A-H1N1pdm09, Flu A-H3N2, Flu B, RSV A, RSV B, PIV 1, 2, 3, AdV RV-Panel B : CoV - OC43, NL63, 229E, HKU1, hBoV, hRV,...