GENETEK BIO PHARMA Providing solutions to genetic diagnostics and human identity

GENETEK Biopharma GmbH Human Identification Kits GTDetector GTXDetector GTYDetector 29 Upcoming Human Identification Kits GTDetector Globe GTDetector Paleo Diagnostic Kits AneuSure® AZFScreen Upcoming Diagnostic Kits HapScreen Kits 23 Animal Identification Kits G TE qu i n e

At GENETEK Biopharma, we pride ourselves in being one of the few firms providing high quality kits and services for both healthcare, research and forensic applications.

GENETEK Biopharma GmbH, is located in the The foundation of the company began with Science city of Berlin-Adlershof: the new Hot- acquiring facility in Adlershof Science Park spot of Science, Technology and Media, in Berlin, – Berlin and restructuring the labs to adapt Germany. The foundation of our company com- molecular biology experiment requirements. prises of scientists and researchers from the Bio- The scope of the company includes Develop- technology and Molecular Biology disciplines. ment, Production, Marketing and Distribution Their experience and advance know-ledge in the field of human...

GTDetector For human profiling in forensic cases, parentage identification and research use GTDetector kit is developed to meet the requirement for global database search and can be used for most populations. This kit consists of 16 STR markers and Amelogenin gene as a sex determination marker, out of which 13 STR markers are CODIS Core loci and 11 STR markers are recommended by the European Network of Forensic Science Institutes (ENFSI). Most importantly, customers can achieve high discrimination power by amplifying highly heterozygous loci SE33 included in the kit. Multiplex analysis of 17...

GTDetector Markers Figure 1: GTDetector Markers showing their respective fluorescent dyes and size ranges. Figure 2: GTDetector markers location on Chromosomes.

Figure 3: A male sample with DNA concentration of 500pg, amplified using the GTDetector Kit and analyzed on Applied Biosystem(TM) 3500xL Genetic Analyzer. Figure 4: A male saliva sample directly amplified from DBC(TM) using the GTDetector Kit and analyzed on Applied Biosystem(TM) 3500xL Genetic Analyzer.

Key Features High level of sensitivity to as low as 0.5ng of input DNA GTDetector can successfully amplify low amounts of DNA. We recommend optimal range from 0.5ng to 5ng of input DNA in the reaction to achieve a full and clear profile Applicable to a variety of DNA sources GTDetector can be applied to a variety of different DNA sources and is even capable of direct amplification using DBC or FTA punches GTDetector Kit comes with easy to use reagents, ~ 90 minutes of hands on time for a lab geneticist. in ~1.5 Hours SA M PLE COMPAT IBILIT Y Direct PCR - no DNA extraction Extracted DNA from variety...

GTXDetectorFor female profiling in forensic and kinship cases GTXDetector consists of 15 X chromosome specific markers to differentiate female profile especially when complimentary markers are needed in complex kinship cases. It can also be useful to identify female genotype in the background of male sample. Multiplex PCR - amplification of 1 GTXDetector markers are designed in such way that distribution of loci covers the whole length of X chromosome (Table 1). Markers heterozygosity and SNP in their primer sites were tested on several hundreds of DNA samples. The GTXDetector multiplex system...

High level of sensitivity to as low as 0.5ng of input DNA Applicable to a variety of DNA sources GTXDetector can be applied to a variety of different DNA sources and is even capable of direct amplification using DBC-punches Xq21.31 Samples to results in a day GTXDetector Kit comes with easy to use reagents, ~ 2 hours of hands on time for a lab geneticist Figure 6: GTXDetector markers location on human X Chromosome Figure 7: A female sample with DNA concentration of 500pg, amplified using the GTXDetector Kit and analyzed on Applied Biosystem(TM) 3500xL Genetic Analyzer.

GTYDetector 29 For human profiling in forensic cases, parentage identification and research use. The GTYDetector 29 is the only kit available with high discrimination power of 27 markers for Y chromosome and compatible with 5 dye detection system. The GTYDetector 29 multiplex system is optimized to amplify 28 markers in a single reaction and these loci are differentiated with 5 dye system using fragment analysis technology. This kit is compatible with ABI 3500/xL and ABI 3130/xl platforms for detection and analysis. The GTYDetector 29 multiplex system was designed to achieve high power of discrimination...

High level of sensitivity to as low as 0.5ng of input DNA GTYDetector 29 can successfully amplify low amounts of DNA, we recommend optimal range from 0.5ng to 5ng of input DNA in the reaction to achieve a full and clear profile Applicable to a variety of DNA sources GTYDetector 29 can be applied to a variety of different DNA sources and is even capable of direct amplification using Samples to results in a day GTYDetector 29 Kit comes with easy to use reagents, ~ 2 hours Figure 9: GTYDetector markers location on human Y Chromosome of hands on time for a lab geneticist. Figure 10: A male sample...

The GTDetector Globe kit is developed to meet requirement for global database search and can be used for most populations. This kit consists of 27 markers, out of which 20 STR markers are CODIS Core loci and 11 STR markers are recommended by the European Network of Forensic Science Institutes (ENFSI). Most importantly, customers can achieve high discrimination power by amplifying most heterozygous loci Penta D, Penta E and SE33 included in the kit. The GTDetector Globe multiplex system is optimized to amplify 27 markers in a single reaction and these loci are differentiated with 6 dye system...

The GTDetector Paleo kit is developed exclusively to amplify highly polymorphic markers from low quality degraded DNA. This kit consists of 11 STR markers and Amelogenin gene as a sex determination marker. These STR markers are also recommended by CODIS. The GTDetector Paleo multiplex system is optimized to amplify 12 markers within size range of 100-300bp in a single reaction and these loci are differentiated with 5 dye system using fragment analysis technology. This kit is compatible with ABI 3500/3500XL and ABI 3130/3130x1 platforms for detection and analysis. Features • Easy to use mix •...