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BLOODchipID Blood Group Genotyping

BLOODchipID Blood Group Genotyping

BLOODchipID Blood Group Genotyping

Product catalog summary
Introduction
Grifols has developed multiplex genotyping tests for detecting red blood cell (RBC) and human platelet antigens to enhance patient safety in blood transfusions. With over seventy years of experience, Grifols prioritizes safety and has innovated blood typing systems for improved transfusion compatibility.

Limitations of Serology
Traditional hemagglutination tests, while effective, can be unreliable in certain situations. Serological results may be inconclusive, requiring multiple methodologies, which is time-consuming and costly.

Advantages of Genotyping
Genotyping directly determines alleles coding for surface antigens, offering advantages in cases such as transfusion-dependent patients, patients with antibodies on RBCs, and those with recent transfusions. It is more practical due to limited availability and high cost of reagent antisera for rare antigens.

Benefits of Genotyping
For blood banks, genotyping improves patient quality of life, reduces hospital admission times, and extends periods between transfusions. It also enhances cost-efficiency and allows for a comprehensive donor database. For hospitals and patients, it reduces adverse reactions and provides faster turnaround times.

Procedure Workflow
The ID CORE XT and ID HPA XT systems analyze polymorphisms to determine RBC and HPA antigens using Luminex technology. These systems are efficient, requiring minimal hands-on time and providing results in under four hours.

Software and Connectivity
BLOODchip® ID Software manages genotyping procedures, ensuring traceability and providing detailed reports. It offers connectivity with laboratory information systems and Luminex, automating result interpretation.

Compliance and Service
The systems comply with European and US regulations for research use. BLOODchip® Service offers genotyping without investment in equipment, providing comprehensive reports and scientific support.

Conclusion
Grifols' genotyping solutions offer a practical and efficient approach to blood group typing, enhancing safety and compatibility in transfusion medicine.
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Catalog excerpts

BLOODchipID Blood Group Genotyping-1

THE MATCH BLOOD TYPING SOLUTIONS Compatible with you

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BLOODchipID Blood Group Genotyping-2

MULTIPLEX GENOTYPING TESTS FOR DETECTION OF RED BLOOD CELL AND HUMAN PLATELET ANTIGENS At Grifols, we know that your primary concern in blood transfusions Recently, DNA-based testing has proved to be an extremely is to ensure patient safety. After seventy years of experience in effective technique that can, in certain situations, offer the field of transfusion medicine we have demonstrated that advantages over current serology techniques. safety is also our number one priority. BLOODchip® is a fast and effective solution for typing the most Blood group compatibility between donor and patient...

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BLOODchipID Blood Group Genotyping-3

How does genotyping overcome current limitations of serology? Molecular analysis for determining blood group phenotypes directly determines alleles that code for surface antigens. In which cases is genotyping a better option? Transfusion dependent patients (with sickle-cell disease, thalassemia or cancer), who are at risk of alloimmunization can benefit from individualized RBCs through extended antigen matching.1 When RBC’s are coated with antibodies. In patients showing a positive direct antiglobulin test due to in vivo sensitization.2 When patients have had recent transfusions, it is difficult...

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BLOODchipID Blood Group Genotyping-4

• ID CORE XT analyzes 29 polymorphisms determining 37 antigens of RBC • 48 tests per kit • Proved accuracy including r's • Based on Luminex technology BLOOD GROUPS Main applications: • Asses the presence/absence of blood groups in chronically and recently transfused patients • Screen routine donors • Select compatible donors for alloimmunized patients • Complement serological panel with further antigen identification SIGNAL DETECTION (LUMINEX)

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BLOODchipID Blood Group Genotyping-5

IDHPAXT • ID HPA XT analyzes 13 polymorphisms determining 12 HPA Systems • 48 tests per kit • Based on Luminex technology Main applications: • Platelet antigen typing in donor and patients • Perform large-scale donor typing for provision of antigen-negative platelets • Help to select compatible platelet donors for refractory or alloimmunized patients • Complement clinical history of alloimmune platelet disorders, such as foetal and neonatal alloimmune thrombocytopenia (FNAIT), post-transfusion purpura and platelet ransfusion refractoriness NOT VALID FOR PRINTING! Low resolution PDF file. For...

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BLOODchipID Blood Group Genotyping-6

BLOODchip® ID Software optimally handles the genotyping procedure and data INTUITIVE COMPREHENSIVE CONFIGURABLE FLEXIBLE WORKFLOW TRACEABILITY BIDS XT provides with plate configuration, kit and enzyme lot registration functions to help users to trace sample, reagents and results Also provides with worksheet print-outs with volumes and guidelines to support users with the procedure DATABASE & MULTIPLE-SEARCH FUNCTION It is a comprehensive data base for samples, clinical information and test results Multiple search functions, including phenotypes and genotypes searching tools, helps users to find...

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BLOODchipID Blood Group Genotyping-7

NOT VALID FOR PRINTING! Low resolution PDF file. For high resolution files, please contact Corporate Communications corporatecomms®grifols.com

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BLOODchipID Blood Group Genotyping-8

BLOODchip® Service is a practical and efficient way to conduct blood group genotyping. No investment or minimum volume of samples is required; simply send your samples to our Reference Laboratory in Medford, US. BLOODchip® Service provides Immunohematology Laboratories: • The possibility of performing tests with the complete • Assistance and scientific support for BLOODchip® product portfolio and the latest challenging cases sequencing technologies An easy and detailed report CLIA* certified procedures and assays guarantees confident results. Please contact Grifols local representative for...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.