DOAC-Stop™
3Pages

DOAC-Stop™ The original DOAC eliminator

DOAC-Stop™ is first of its kind to extract all types of new Direct Oral Anti-Coagulants (DOACs) including dabigatran, edoxaban, betrixaban, rivaroxaban, apixaban and argatroban from test plasmas with minimal effect on plasma proteins involved in the clotting mechanism. It absorbs up to an estimated 2,000ng/ml of any DOAC in less than 10 minutes. There is negligible interference with vitamin K antagonists or heparinoid anticoagulants. Plasmas treated with DOAC-Stop™ can be used for valid factor assays and in testing for thrombotic risk. In particular it can prevent false LA positive results...

REFERENCES: 1. Exner T, et al. The effect of DOACs on laboratory tests and their removal by activated carbon to limit interference in functional assays. International Journal Laboratory Hematology 2020;00:1–8. 2. Favaloro E, et al. Neutralising rivaroxaban induced interference in laboratory testing for lupus anticoagulant (LA): A comparative study using DOAC Stop and andexanet alfa. Thrombosis Research 180 (2019) 10–19 3. Slavic L, et al. Evaluation of the DOAC-Stop Procedure by LC-MS/MS Assays for Determining the Residual Activity of Dabigatran, Rivaroxaban, and Apixaban. Clinical and...