DOAC-Stop™
DOAC-Stop™
DOAC-Stop™ is a pioneering product designed to eliminate all types of Direct Oral Anti-Coagulants (DOACs) from test plasmas. It effectively removes DOACs such as dabigatran, edoxaban, betrixaban, rivaroxaban, apixaban, and argatroban, while minimally affecting plasma proteins involved in clotting.
Specifications
- Absorbs up to 2,000ng/ml of any DOAC in under 10 minutes.
- Negligible interference with vitamin K antagonists or heparinoid anticoagulants.
- Suitable for valid factor assays and thrombotic risk testing.
- Prevents false positive results in lupus anticoagulant testing.
Procedure
The process involves three simple steps: Add, Mix, and Centrifuge. The product is stored at room temperature and has a shelf life of three years.
Performance
A graph illustrates the efficiency of DOAC-Stop™ in removing DOACs, showing significant reduction in APTT seconds after treatment.
Product Variants
- Available in packs of 50 or 100 mini-tabs.
- CE Marked and IVD (ARTG Listed) status.
Company Background
Founded by Dr. Thomas Exner in 2004, Haematex focuses on enhancing coagulation lab efficiency through innovative diagnostic reagents.
References
Several studies and articles are cited, demonstrating the effectiveness and application of DOAC-Stop™ in various laboratory settings.
Catalog excerpts
DOAC-Stop™ The original DOAC eliminator
Open the catalog to page 1
DOAC-Stop™ is first of its kind to extract all types of new Direct Oral Anti-Coagulants (DOACs) including dabigatran, edoxaban, betrixaban, rivaroxaban, apixaban and argatroban from test plasmas with minimal effect on plasma proteins involved in the clotting mechanism. It absorbs up to an estimated 2,000ng/ml of any DOAC in less than 10 minutes. There is negligible interference with vitamin K antagonists or heparinoid anticoagulants. Plasmas treated with DOAC-Stop™ can be used for valid factor assays and in testing for thrombotic risk. In particular it can prevent false LA positive results due...
Open the catalog to page 2
REFERENCES: 1. Exner T, et al. The effect of DOACs on laboratory tests and their removal by activated carbon to limit interference in functional assays. International Journal Laboratory Hematology 2020;00:1–8. 2. Favaloro E, et al. Neutralising rivaroxaban induced interference in laboratory testing for lupus anticoagulant (LA): A comparative study using DOAC Stop and andexanet alfa. Thrombosis Research 180 (2019) 10–19 3. Slavic L, et al. Evaluation of the DOAC-Stop Procedure by LC-MS/MS Assays for Determining the Residual Activity of Dabigatran, Rivaroxaban, and Apixaban. Clinical and Applied...
Open the catalog to page 3All Haematex catalogs and technical brochures
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Phospholipids3 Pages
Inhibitor Tubes3 Pages
Go-DOAC™3 Pages
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