Introduction
The document introduces Go-DOAC™, a rapid and sensitive test for measuring direct oral anticoagulants (DOACs). It highlights the challenges in quantifying DOACs using traditional methods and presents Go-DOAC™ as a solution.

Product Specifications
Go-DOAC™ is a modified phospholipid-rich Russells viper venom reagent. It is highly sensitive to DOACs, resistant to most lupus inhibitors and heparins (up to 1u/ml), but sensitive to warfarin and defects in the common coagulation pathway. The product is freeze-dried, stable for one year after reconstitution at 2-8°C, and compatible with Thrombin Time on an analyzer.

Testing Methodology
The document suggests using the lupus anticoagulant-resistant dilute Russells viper venom test (dRVT-LR or "Confirm") for testing all DOACs. This method is sensitive to both thrombin and factor Xa inhibitors and is not affected by extraneous variables like heparins or low factor VIII, IX, or XI levels.

Performance and Compatibility
Go-DOAC™ demonstrates high sensitivity for all new DOACs, including dabigatran, apixaban, rivaroxaban, and edoxaban. It is resistant to heparin and low factor VIII levels, making it a reliable choice for accurate DOAC measurement.

Company Background
Haematex, founded by Dr. Thomas Exner in 2004, focuses on improving coagulation lab efficiency through innovative diagnostic reagents. The company adheres to high standards of quality and safety in its product design, manufacturing, and distribution.

Contact Information
Email: [email protected]
Phone: (+61) 2 9482 2288
Address: Suite 9/17 King Rd, Hornsby 2077 NSW, Australia
Website: www.haematex.com

Conclusion
Go-DOAC™ offers a reliable and efficient solution for measuring DOACs, addressing the limitations of current testing methods and supporting better clinical decision-making in managing thrombosis and haemorrhage.