Caution: Federal (US) law restricts this device to sale by or on the order of a physician or licensed healthcare practitioner. Laser-assisted Hatching and Laser-assisted Biopsy are not recommended for use in all IVF patients. Clinical Software Features Image Capture Freehand Text/Drawing/Measuring Tools ! Save images with or without the target overlay ! Add custom text using any available font type and style, in any system color ! Capture image automatically upon laser firing ! Save images with File Name Stamp and auto-labels ! Measure any aspect of the captured image ! Magnification value saved with image Integrated Database and Reporting Real-time and Time-lapse Video Capture ! Draw ellipses, rectangles or lines, select outline thickness and color ! Automatic image naming using user-defined root name or report name ! Save patient and embryo information [Time-lapse video capture should not be used for therapeutic or diagnostic procedures.] ! Save data from multiple cycles ! Record real-time or time lapse video of the current image field at the touch of a button Clinical Laser Systems ! Design unlimited reports ! Files saved as standard .mp4 video format ! Ability to select any stored data for output to ASCII file ! Automatic video file naming using user-defined root or report name Image Auto-labeling ! User-defined auto-labeling allows creation of multiple labels ! Choose from date, time, objective information and report input values (such as patient name and embryo ID) ! Designate specific location of each label on image Clinical Laser System Components ! 40x LYKOS objective or ZILOS-tk module with built-in Class 1 laser diode (1460 nm) ! Choice of small form factor desktop system with 24” HD widescreen monitor or laptop system ! RED-i Target Locator (LYKOS only) ! Remote foot switch for firing laser ! Proprietary laser software ! Adapters for installation on inverted microscopes ! Laser controller box ! High resolution color digital camera, with de-magnifier c-mount adapter. Image courtesy Assisted Conception Unit, Glasgow Nuffield Hospital HAMILTON THORNE 100 Cummings Center, Suite 465E, Beverly, MA 01915 USA 978-921-2050, 800-323-0503, Fax: 978-921-0250 [email protected], www.hamiltonthorne.com Image courtesy Michael Tucker, PhD, Shady Grove Fertility Reproductive Science Center Image courtesy Georgia Kokkali, PhD Genesis Athens Clinic Trophectoderm Biopsy Blastomere Biopsy Laser-Assisted Hatching HAMILTON THORN

LYKOS & ZILOS-tk Overview Version 6 Laser Software & Hardware The hardware and software features of the LYKOS and ZILOS-tk clinical lasers work together seamlessly to provide sophisticated yet easy-to-use laser systems for the ART facility. The LYKOS represents the next generation of clinical lasers from Hamilton Thorne, with both the laser and RED-i® target locator built into a customized 40x objective. Our legacy ZILOS-tk represents a cost-effective alternative for those who do not require the RED-i or multipulse features. The HT Laser 6 software provides the same precise, easy-to-use laser-assisted...

LYKOS & ZILOS-tk Overview Version 6 Laser Software & Hardware The hardware and software features of the LYKOS and ZILOS-tk clinical lasers work together seamlessly to provide sophisticated yet easy-to-use laser systems for the ART facility. The LYKOS represents the next generation of clinical lasers from Hamilton Thorne, with both the laser and RED-i® target locator built into a customized 40x objective. Our legacy ZILOS-tk represents a cost-effective alternative for those who do not require the RED-i or multipulse features. The HT Laser 6 software provides the same precise, easy-to-use laser-assisted...

Caution: Federal (US) law restricts this device to sale by or on the order of a physician or licensed healthcare practitioner. Laser-assisted Hatching and Laser-assisted Biopsy are not recommended for use in all IVF patients. Clinical Software Features Image Capture Freehand Text/Drawing/Measuring Tools ! Save images with or without the target overlay ! Add custom text using any available font type and style, in any system color ! Capture image automatically upon laser firing ! Save images with File Name Stamp and auto-labels ! Measure any aspect of the captured image ! Magnification value saved...