Surgiclean Fibril Absorbable Hemostat Oxidized Regenerated Cellulose QS001
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j. Hemostatic effect of oxidized regenerated cellulose hemostatic material in porcine coronary artery wound model [J]. Chinese Journal of Tissue Engineering Research, 2024,28(10):1490-1496. [2] Li Wei, Wang Lingshuang, Sun Weiqing. Research on the clinical application and mechanism of action of cellulose-based hemostatic materials [|].Contemporary Medicine Forum, 2019, 17(22): 13-15. [3] Dias G J, Peplow P V, Teixeira F. Osseous regeneration in the presence of oxidized cellulose and collagen [|]. Journal of Materials Science Materials in Medicine, 2003,14(9):739. [4] ZHANG Mei, WANG Chunren. Study on Hemostatic Mechanism of Water-Soluble Hemostatic Textile Materials [|]. Journal of Textile Research, 1997,18(5):4-8. [5] Huang Wei, Xu Xiaohui, Guo Liping. Effects of three-dimensional structure and degree of oxidation on the performance of hemostatic material of oxidized regenerated cellulose at C6 position[|]. Polymer Bulletin, 2016, 9:71-78 [6] Wang Lingshuang, Tong Jianxing, Zhao Zhezhe, etc. Efficacy and safety evaluation of an absorbable hemostatic filament[|]. Zhejiang University Journal (Medical Edition), 2021, DOI10.3724/ZDXBYXB-2021-066 [7] Clinical trial of absorbable oxidized regenerated cellulose fibrils. Guangxing Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Sir Run Run Shaw Hospital (SRRSH) affiliated with the Zhejiang University School of Medicine, Tongde Hospital of Zhejiang Province. 2020 SURGICLEAN® FIBRIL ABSORBABLE HEMOSTAT ■ 4 invention patents ■ Rapid hemostasis with zero residue ■ Easily shaped to address each particular bleeding site ■ Three-dimensional structure to achieve effective hemostasis HANGZHOU SINGCLEAN MEDICAL PRODUCTS CO.,LTD No. 125, No. 10 Street (East), Qiantang Area, Hangzhou, Zhejiang ,China 0086571-63431868-8019 marketing@singdean.net www.singdean.net

SURGICLEAN® INTRODUCTION MECHANISM OF HEMOSTASIS This next generation Surgiclean Fibril Absorbable Hemostat (Oxidized Regenerated Cellulose) is sterile absorbable non-woven fabric prepared by oxidation of regenerated cellulose. Apply Surgiclean to bleeding areas With non-woven fabric that separates into layers and can be pulled apart and manipulated for precise placement. It could be more convenient than the knitted form for hard to reach or irregularly shaped bleeding sites. non-regenerated oxidized cellulose gauze INDICATIONS FOR USE This product is suitable for various surgical...

PRODUCT CHARACTERISTICS Three-dimensional structure of Surgiclean® , effective and rapid hemostasis Loose network porous structure which can improve water absorption, accelerate gelation rate and dissolution rate [5] and ensure large contact area. PRODUCT CHARACTERISTICS It can be layered and easy to be shaped for complex wounds It can be separated into multiple layers to meet the needs of different wounds After contacting with blood, the single fiber swells obviously and Surgiclean® can absorb blood 20-30 times its own mass, just like S Product [6]. It can be easily shaped to address each...

CLINICAL DATA ANIMAL TESTING Animal Testing: Safety (Pathological Observation) Hemostatic Effective Rate Through the clinical trials of open surgery and laparoscopic surgery, the subjects were divided into the test group (Surgiclean® ) and the control group (S product). The test results showed that the test group (N=144) and the control group (N=144) have significant hemostatic effect, the hemostatic effective rate of the test group (N=144) and the control group (N=144) with 3 minutes are both 100%. Pathological observation on the liver, heart, lung, kidney, spleen and chest of minipigs in each...

METHOD OF USE Animal Testing: Degradability According to the size and shape of the wound, the doctor can take appropriate size and layers of Surgiclean® to cover the wound. Study on the Degradability of Surgiclean® in Minipigs The degradation rate of oxidized regenerated cellulose increased with the prolongation of degradation time. 2 days after the implantation, the test group (Surgiclean®) and the control group (S Product) decreased by 61.80% and 48.25% respectively; Degradation rate 3-4 days after the implantation, the degradation rate of the test group (Surgiclean ® ) was comparable to...

Surgiclean Fibril Absorbable Hemostat (Oxidized Regenerated Cellulose) Surgiclean® is suitable for various surgical operations when ligation or other conventional control methods are ineffective or inoperable, as an adjunctive hemostatic device to control the bleeding of capillaries, veins and small arteries. Surgiclean® Fibril Absorbable Hemostat Pliable and can be easily shaped and molded to fit the wound or bleeding site, providing better coverage and contact with the affected area. Surgiclean® Powder Absorbable Hemostat Fast for Broad, Irregular Wound Surfaces and in Hard-to-Reach Areas...