VERTICAL DIFFUSION CELLS The Hanson Vertical Diffusion Cell (VDC) is an ideal tool for the study, development, and quality control of topical preparations. Made of inert borosilicate glass, the VDC is designed for accuracy and ease of use with over thirty years of rigorous industry, university, and regulatory application and collaboration. Hanson VDCs are compatible with a number of membrane types including synthetic, animal skin, cadaver skin, and Strat-M® membranes. Hanson VDCs include individualized serial numbers and are readily available in three convenient sizes. (STANDARD CELL TOP INCLUDED WITH EACH HANSON VDC) Receptor Chamber Sampling Port Donor Chamber (membrane not shown) Water Jacket Media Replace Port Circulator Ports Bubble Trap Helix™ Stirrer Ideal for topical and transdermal drug delivery formulations, opthalmics, cosmetics, skin care products, and pesticides “Occluded” design seals the donor from air to minimize any back-diffusion from sampling Water jacket covers entire receptor chamber for temperature consistency Bubble Trap catches bubbles before they enter VDC and affect the diffusion rate Circulator ports provide connections to ensure cell-to-cell temperature uniformity Shorter sampling port reduces dead volume Clamp Assembly holds the cell top in place while providing even cell-top pressure Purchase of a Hanson VDC includes Standard Cell Top and Clamp Assembly Automated sampling capability with the Vision® Microette™ diffusion test system USP <1724> compliant 9810 Variel Avenue • Chatsworth, CA 91311 USA • TOLL FREE: 800.821.81.65 • PHONE: 818.882.7266 • FAX: 818.882.9470 • www.hansonresearch.com 99-310-044 Rev. 8-15 (1 of 2 - front) | © Hanson Research Corp | This informatio

VERTICAL DIFFUSION CELLS Hanson VDCs are available in the three standard sizes below in amber or clear glass, or in custom sizes upon request. The 7 mL “Standard” VDC is recommended by the US FDA for topicals. HANSON VDC COLORS & SIZES ORDERING INFORMATION For more information, please contact your local Hanson representative or email us at [email protected] VERTICAL DIFFUSION CELLS (VDC) (includes Standard Cell Top, Helix Kit, and Clamp Assembly) 58-001-450 Clamp Assembly 58-001-451 Vertical Diffusion Cell, 9 mm orifice, 4 mL vol, “Small” 58-001-452 Vertical Diffusion Cell, 9 mm orifice,...

VERTICAL DIFFUSION CELLS STANDARD CELL TOP OPEN CELL TOP WITH CAP The Standard Cell Top is included with a Hanson VDC. It is The Open Cell Top with Cap is easily adaptable to the Hanson occluded to minimize back diffusion during the sampling VDC. The cap can be removed between sampling time points process. A membrane is applied to one side of the dosage to add or remove material. It is best used for less viscous wafer, and the dosage is applied to the opposite side in the materials because the cell top can be assembled prior to donor chamber. This cell top is best used for viscous materials applying...

VERTICAL DIFFUSION CELLS CUSTOM APPLICATIONS Novel dosage forms are being researched everyday throughout various scientific industries. Hanson Research's team of development engineers can design special cells and cell tops to accommodate custom applications such as in-situ fiber optics, non-viscous dosage forms, permeation through fingernails and toenails, iontophoresis and much more. Hanson can support your unique application. ORDERING INFORMATION For more information, please contact your local Hanson representative or email us at [email protected] STANDARD CELL TOP SPARE PARTS 58-001-507...