ElProScan The Ultimate Scanning Probe Microscope System
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ElProScan The Ultimate Scanning Probe Microscope System łł Going beyond classical SECM

HE<A a division of Harvard Bioscience. Inc. For over 45 years HEKA has designed and manufactured sophisticated instrumentation and software for biomedical and industrial research applications. Through the years, HEKA has achieved an unparalleled reputation for precision and quality. Medical, pharmaceutical and industrial research facilities world-wide rely on HEKA ingenuity for their discoveries. While there have been many changes in research, instrumentation, and software, our commitment to bring innovative technology to our customers remains constant. HEKA is a select group of engineers,...

Micro- and Nanopipette Techniques 6 Shear Force Sensing 7 Techniques for Corrosion Science 8 ElProScan Components and Features 9 Integrated Microscope Optics 10 Fluorescence and Ratiometric Imaging 11 Single Cell Imaging 12 Study of Photoelectrochemical Reactions 13 Optical Microscopy and Micro-Spectroscopy 14 System Components and Specifications 16 Popular Accessories for ElProScan System 19 Further Reading Additional information such as manuals, technical specifications and PDF brochures for most HEKA products listed in this catalog can be downloaded directly from our web site at...

The HEKA ElProScan is a unique electrochemical scanning probe microscope (e-SPM) system, which employs an ultramicroelectrode and/or nano-/micropipette as a scanning probe to perform in situ high-resolution microscopic imaging of local reactivity and topography of various types of samples and materials. ElProScans are offered in different models and various configurations to tackle a wide range of cutting edge and engineering applications. ♦♦ Micro-Sensors ♦♦ Electrophysiology & Single-Cell Imaging ♦♦ Energy Conversion & Storage ♦♦ Corrosion Processes & Protective Coatings Multifunctional...

SECM Techniques Scanning Electrochemical Microscopy (SECM), with decades of development and evolution, delivers a classical group of electroanalytical scanning probe techniques, capable of imaging and studying substrate topography and local reactivity with high spatial and electrochemical resolutions via the non-contact working electrode, an ultramicroelectrode with diameter ranging from approximately 20 nm to 25 µm. The ElProScan system has been considered by our worldwide users the best-in-class SECM, covering not only the classical working modes, but also many unique advanced scanning...

Micro- and Nanopipette Techniques In addition to SECM with a scanning microelectrode as probe, a unique group of e-SPM techniques employ micro-/nanopipettes as a scanning probe, which is regulated via detecting its ionic current at the tip end for distancecontrol between the probe and substrate to achieve nanoscale topographical mapping of soft and delicate surfaces. Such a micro-/nanopipette probe can also be modified and used as a bi-functional probe to detect faradaic current (i.e. surface reactivity) from the tip end, which is either submerged in bifunctional electrolyte or operated in...

Shear Force Sensing To overcome the drawbacks in traditional constant-height mode of SECM, Shear Force based height regulation has been proven to be the most effective and reliable mechanism for the advanced constant - distance scan mode, in which the probe scans along the sample’s contour keeping a constant tip-to-substrate distance and the tip current signals are thus decoupled from the substrate’s topographical complications. The HEKA Shear Force Extension allows simultaneous recording of topography and current signals in constant-distance regulation of SECM and SICM/SECCM....

Techniques for Corrosion Science In material sciences, the study of degradation and corrosion processes is of interest. SECM as well as micropipette techniques have been applied to investigate corrosion kinetics (generation-collection mode of SECM), local corrosion potentials (SECCM) and localized impedance measurements (SMCM). The combination with Shear Force sensing allows constant-distance scans. Studying localized corrosion processes at alloys by SECM The addition of Ti to ferritic stainless steel inhibits intergranular corrosion but takes part in the initiation of other localized...

ElProScan Components and Features The ElProScan system consists of three main modules: the mechanical positioning stage, the dual-channel electrochemical workstation, and a real-time controller. Each of these functional modules is designed to be easily customized to meet your particular application requirements. Model-specific modules include a synchronized optical imaging system and the Shear Force extension. High-Precision Positioning System • The ElProScan 3 platform utilizes the highest quality closed-loop controlled multi-axis motorized positioning system. A linear encoder (2.5 nm...

Integrated Microscope Optics HEKA’s ElProScan allows the integration of an inverse microscope into the scanning platform enabling a wide range of extended techniques. Advanced scanning probe system from the top (XYZ) Synchronized photon excitation and detection system from the inverted bottom (F) An illustration of ELP 3 system with epi-fluorescence optics The Unique Modular Microscope Provides an Extendable Platform Reflection Image • • • Transmission Image Combined Image The system’s built-in inverted modular microscope supports bright/dark field imaging, as well as many types of high-end...

Fluorescence and Ratiometric Imaging HEKA SmartLUX for Synchronized Imaging Control • • SmartLUX software allows the user to perform optical image acquisition and electrochemical recordings simultaneously. The timing of fluorescence excitation by the light source, the camera exposure and the electrochemical data acquisitions are all precisely synchronized by the software. SmartLUX is an ongoing HEKA research & development project. The current product features high temporal resolution and exact correlation among fluorescence data and electrophysiological & electrochemical data. Correlation...