KNOW YOUR PATIENT – AND REDUCE PJI RISK

– KNOW YOUR PATIENT … APPROX. 60 % OF PATIENTS AGED ≥ 65 YEARS ARE AT HIGHER RISK FOR INFECTION*1–3 rthroplasty patients benefit from an integrated preventive approach according to infection A risk stratification1 igh risk patients require intensified prevention measures that include the use of high-dose H dual antibiotic-loaded bone cement4 * Definition of high risk: at least 2 risk factors such as diabetes, cardiovascular disease, obesity, previous infection, smoking, older age, revision surg

… AND REDUCE PJI RISK. Preventing surgical site infection and PJI following arthroplasty is challenging. Measures include both, optimisation of surgical procedures as well as peri-operative antibiotic prophylaxis.4 An integrated and effective preventive approach reduces PJI risk in patients with risk factors. Dual antibiotic-loaded bone cement COPAL® G+C can be one part in this set of measures.1,5 Skin preparation and wound irrigation Management of anaemia & malnutrition Dual antibioticloaded bone cement Perioperative blood management PJI prevention3,4,6 Preoptimization of comorbidities (e.g....

Dual antibiotic-loaded bone cement with Gentamicin and Clindamycin Indicated for implant fixation Very broad spectrum of activity against most pathogens clinically relevant for PJI In combination, both antibiotics may target up to 90 % of all pathogens typically found in PJI Effective against anaerobic pathogens amongst others High local antibiotic concentrations with low systemic load Infection prevention as part of risk-adapted approach SOURCES 1. Sanz-Ruiz P, Berberich C. Infection Risk-Adjusted Antibiotic Prophylaxis Strategies in Arthroplasty: Short Review of Evidence and Experiences of...