Fast and effective SAVES PROCESSING TIME PALACOS® fast R+G is a fast setting, high viscosity bone cement containing gentamicin. Unlike other fast setting bone cements, PALACOS® fast R+G is formulated without a waiting phase during the mixing process. Compared to PALACOS® R+G, the working time for PALACOS® fast R+G can be shortened up to 37 %.(1) SIMPLY MIX AND APPLY WITH NO WAITING TIME PALACOS® fast R+G ■ Mixing ■ Waiting ■ Application ■ Setting ■ Reduction of total working time Test conditions: not pre-chilled bone cement, manually mixed EFFECTIVE RELEASE OF ANTIBIOTICS The high risk period for developing a periprosthetic infection is within the first 48 hours after implantation of a prosthesis.(2) Therefore an initial high dose of locally released antibiotic can support antibiotic prophylaxis.(3) Based on the proven polymer structure of PALACOS®, the broad spectrum antibiotic gentamicin is released in large amounts from PALACOS® fast R+G.(4) Thus PALACOS® fast R+G can be used to support prophylaxis for periprosthetic infections. PALACOS ® FAST R+G ELUTION RATE Highest risk of infection PALACOS® fast R+G (1.25 % gentamicin) 0 1 Modified from Caraan et al., 2017 (1) IFU PALACOS® fast R+G, 2013. (2) Gristina AG, Naylor P, Myrvik Q. Infections from biomaterials and implants: a race for the surface. 1989; 205–224. (3) K ühn KD. PMMA Cements. Springer 2014; 147, 218. (4) Caraan N et al. Role of fast-setting cements in arthroplasty: A comparative analysis of characteristics, Worl

Good mechanical properties FATIGUE STRENGTH 15 12 HIGH FATIGUE STRENGTH The main concern for both doctor and patient is achieving a long prosthesis life time. Stable fixation of the prosthesis is therefore essential to prevent aseptic loosening and avoid revision surgery. The mechanical performance of the bone cement is reduced as a rule by low fatigue strength.(3) PALACOS® fast R+G has a high fatigue strength, which can help increase the lifespan of the prosthesis fixation.(4) at a glance Up to 37 % faster working times* – no waiting time Effective release of gentamicin for antibiotic prophylaxis...