Discover the Label-Free Platform From HORIBA Scientific Get The Most Out of Your Instrument Simplicity and Flexibility Combined OpenPlex can work with different optional flow cells to give you more flexibility. These accessories can be used to work in a static mode (no flow) or to combine SPRi with other techniques such as Fluorescence or Electrochemistry. 1 2 3 4 • ifferent fluidic cell D configurations • Coupling with other techniques • Quick data analysis • nstant data reporting I • Affinity determination SPRi Software Suite The powerful software suite of OpenPlex allows you to acquire data, analyze results and generate reports automatically. • SPRi-View: Intuitive instrument control software for easeof-use that guides you through all the different steps of the measurement • SPRi-Analysis: Quantitative and report analysis to track all your experiments • ScrubberGen (optional): Advanced analysis to fit data and determine kinetic parameters "We are able to generate consistent results that enable us to identify full binding coefficients for multiple candidate aptamer sequences simultaneously. The instrument […] has become one of the most essential tools that we have." Dr. G. Penner, NeoVentures Biotechnologies, Canada Drug Discovery & Development Cell Science Flexible Surface Functionalization Multiplex Label-Free Interaction Analysis www.horiba.com/spri [email protected] Follow Us This document is not contractually binding under any circumstances - Printed in France - ©HORIBA FRANCE 03/2017 1: tandard Flow Cell for SPRi measurements S 2: Window Flow Cell for fiber-optic coupling with Raman or fluorescence 3: Cuvette Cell for static measurements or in combination with electrochemistry 4: 2-Cavity Cell for static measurements Open Research Platform for Kinetics & Affin

OpenPlex Get information about: • Kinetics • Affinity • Specificity • Concentration • Relative binding Open Research Platform for Fast and Easy Kinetic Interaction Monitoring Biosensor Development - Biomolecule Detection SPRi Technology for Real-Time Label-Free Biomolecular Interactions Gold nanostructures or quantum dots can increase OpenPlex sensitivity for detecting biomolecules. Here, the combination of nanotechnologies and SPRi allows the detection of bacterial RNA (picomolar concentrations). OpenPlex uses Surface Plasmon Resonance imaging (SPRi) to follow label-free binding events in real-time....