Q-graft®

Q-graft®

Q-graft®

Product catalog summary
Overview
The document provides detailed information about the Q-graft® system, a medical device developed by Human Med AG for the intraoperative separation and concentration of adipose-derived stem cells (ASC) and stromal vascular fraction (SVF) cells. This system is designed for use directly on the sterile operating room (OR) instrument table, facilitating point-of-care applications without the need for laboratory transfer.

Key Features
  • Efficiency: The Q-graft® system allows for the rapid and efficient separation and concentration of viable regenerative cells directly in the OR.
  • Closed System: The process is conducted in a sterile, closed system, minimizing contamination risks.
  • Point-of-Care: Eliminates the need for external laboratory processing, enabling immediate use of harvested cells.
  • Temperature Control: The system maintains the lipoaspirate at 38°C for optimal tissue dissociation.

Technical Specifications
  • Q-graft® Control: Dimensions are 25 x 20 x 15 cm, weight 1600 g, with a voltage range of 100-240 V.
  • Q-graft® Collector: Dimensions are 14.2 cm in diameter and 40 cm in height, weight 540 g, with a maximum fill volume of 200 ml.
  • Process Duration: The entire process of fat harvesting and SVF cell separation takes approximately one hour.

Procedure Phases
  1. Preparation: Set up the Q-graft® system on the sterile OR table.
  2. Collection: Lipoaspirate is collected and concentrated in the Q-graft® collector.
  3. Incubation: The lipoaspirate is mixed and incubated at 38°C for 45 minutes.
  4. Cell Separation: SVF cells are isolated through cross-flow filtration.
  5. Collection: The lipid-free SVF cell suspension is extracted via the CELLS port.

Recommendations
  • Using a centrifugation device can enhance SVF cell concentration.
  • Collagenase (Humanase®) can be used to increase cell yield, though it is optional.

Applications
  • The Q-graft® system is suitable for both clinical and research settings, providing a standardized method for harvesting regenerative cells.
  • It supports the production of mesenchymal stem cells in research laboratories.

Conclusion
The Q-graft® system by Human Med AG represents a significant advancement in the field of regenerative medicine, offering a streamlined, efficient, and sterile method for harvesting adipose-derived regenerative cells directly in the operating room.
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Catalog excerpts

Q-graft®-1

Leading in water-jet technology Intraoperative separation and collection of adipose regenerative cells An innovator and leader in water-jet surgery, HUMAN MED® is the world’s first and foremost manufacturer of water-jet assisted aesthetic devices. Building on a long history of success in the fields of general surgery, urology and neurosurgery, where gentle water-jet tissue dissection is essential, in 2004 HUMAN MED® turned its vision to the aesthetics field. The launch of the company’s innovative body-jet®, a waterjet based infiltration, irrigation and aspiration system for removing unwanted body fat has helped to usher in a fundamentally new approach to lipoplasty and natural fat harvesting. The new unique Q-graft® system for the intraoperative harvesting of regenerative cells during liposuction will provide exciting options for adipose stem cell research and new therapies. for intraoperative separation and concentration of adipose derived stem cells In the research laboratory for research purposes and production of mesenchymal stem cells In the laboratory it can help simplify the open, labor-intensive manual tasks associated with laboratory-based SVF and adipose stem cell isolation, concentration and culture. Technical details Q-graft® collector Dimensions: 14,2 (ø) x 40 (H)  cm Weight: 540 g Aspirate volume/Lipocollector function: 75 ml Maximum fill volume upper chamber: 200 ml Volume of SVF cell suspension: 20 ml Vacuum supply: -500 mbar Mixing Frequency: 15/min Rotation during cross-flow filtration: up to 480/min Control temperature during incubation: 38 °C Product / Designation Q-graft® control Q-graft® collector Q-graft® is a registered trademark owned by Human Med AG, Germany. Q-graft® technology is protected by U.S., European and other patents. QUALITY Highly efficient SVF cell separation and concentration right on the sterile OR instrument table Q-graft® control Dimensions: 25 (H) x 20 (T) x 15 (B) cm (without Q-graft® collector) Weight: 1600 g Voltage: 100-240 V (wide-band power supply) Protection class: II Human Med AG Wilhelm-Hennemann-Str. 9 19061 Schwerin Germany © Human Med AG. 05/2019 HMEN9001022_1 QUANTITY High yield of viable regenerative cells (SVF and ASC) Q-graft® is used on the sterile OR instrument table in the operating/procedure room during liposuction, or in the research laboratory, for standardized separation and concentration of high numbers of viable SVF (stromal vascular fraction) cells in a sterile closed system. QUICK Fast fat harvesting and SVF isolation in one

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Q-graft®-2

The unique advantages of the Q-graft® SVF cell harvesting at the point-of-care • AST AND EFFECTIVE F Separation, concentration and collection of high numbers of viable, lipid-free regenerative cells (SVF, ASC, MSC). Research and development Extensive research work in collaboration with renowned medical universities has been the basis for the development of the Q-graft® system. Through this, cutting-edge technologies for the separation and concentration of adipose derived regenerative cells in a compact closed system have been enabled, which are used on the sterile OR i nstrument table in the...

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