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SYNTHERA® + BETTER, SMARTER, STRONGER.

SYNTHERA® + BETTER, SMARTER, STRONGER.

SYNTHERA® + BETTER, SMARTER, STRONGER.

Product catalog summary
Introduction
Synthera®+ is an advanced radiosynthesis module developed by IBA, designed to enhance radiopharmaceutical production. With over 650 units installed globally, it offers increased capacity, reliability, and flexibility, making it a preferred choice for radiopharma producers.

Specifications and Features
  • Compact Design: Synthera®+ is the most compact module available, allowing for space optimization in radiopharmacies.
  • Integrated Fluidic Processor (IFP™): Central to its operation, the IFP™ handles all synthesis steps, preventing cross-contamination and aligning with (c)GMP requirements.
  • Software Platform: A single software platform controls multiple modules, integrating HPLC for purification and supporting customized applications.
  • Multi-Run Capability: Up to 12 independent radiosyntheses can be performed without opening the hot cell, enhancing efficiency and safety.

Production Capabilities
Synthera®+ supports the production of various radiopharmaceuticals, including FDG, NaF, FLT, FCH, FMISO, and Ga-68 peptides. It allows for multiple tracer production in a single hot cell, maximizing output and minimizing downtime.

Software and Compliance
The Synthera®+ software is user-friendly, open-source, and compliant with 21 CFR part 11, ensuring full traceability and regulatory adherence. It offers remote access for diagnostics and maintenance.

Accessories and Extensions
Synthera®+ is an accessory-based platform, allowing for gradual enhancement of functionalities. The Synthera® Extension and HPLC provide additional capabilities for complex processes and purification.

Reliability and Maintenance
All electronic components are placed outside the hot cell to reduce radiation exposure, increasing the system's lifespan and reducing maintenance needs.

Conclusion
Synthera®+ represents a significant advancement in radiopharmaceutical production technology, offering a compact, efficient, and flexible solution for modern radiopharmacies. Its integration with IBA's IntegraLab® system further enhances its utility in establishing compliant production centers.
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Catalog excerpts

SYNTHERA® + BETTER, SMARTER, STRONGER.-1

BETTER, SMARTER, STRONGER.

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SYNTHERA® + BETTER, SMARTER, STRONGER.-2

With more than 650 units installed worldwide, the Synthera® family has proven to be highly efficient and trustworthy. Now, through its program of continuous innovation, IBA has redesigned Synthera® to meet and exceed the ever-growing customer expectations. The result is the new Synthera® +, giving radiopharma producers more capacity, more potential and more reliability. Synthera®+ is the most compact radiosynthesis module on the market. For increased flexibility, different combinations of Synthera®+ modules and accessories can be installed in the same hot cell. 650+ BETTER, SMARTER, STRONGER....

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SYNTHERA® + BETTER, SMARTER, STRONGER.-3

BETTER MULTIPLE RUNS OF MULTIPLE TRACERS MULTIPLE TRACERS PRODUCTION Ready-to-go radiopharmaceuticals COMMERCIALLY AVAILABLE RADIOPHARMACEUTICALS ONE SOFTWARE PLATFORM The software integrates multiple-module control. Several units controlled by one PC only. Up to 12 independant radiosyntheses of multiple tracers can be performed with 3  Synthera®+ equipped with the IFP™ Loader without opening the shielded environment. Synthera®+ has the smallest footprint on the market, which allows the highest level of space optimization ever reached in radiopharmacies. INTEGRATED SYNTHERA®+ HPLC On-line liquid...

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SYNTHERA® + BETTER, SMARTER, STRONGER.-4

MAX EASE OF USE AND THE HIGHEST COMPLIANCE FREE ACCESS TO PRODUCTION RECIPES Synthera® Software Library of Compounds Online Because software is a key component in a product, Synthera®+ software was designed to enhance users experience in routine production as well as research. The Library of Compounds allows the User’s Community to share and exchange radiochemistry applicationprotocols on Synthera® family of products. Synthera® users can simply download the scripts (recipes) from other research laboratories and manufacturers worldwide. There is no reason to start from scratch when others have...

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SYNTHERA® + BETTER, SMARTER, STRONGER.-5

SMARTER ACCESSORY-BASED PLATFORM Synthera®+ is the most cost and space-efficient solution due to its multi-run capability, increased performance with high yield, minimal hot cell investment and optimized maintenance. Synthera®+ is an accessory-based platform allowing you to start from a basic setup then add functionalities over time, ensuring that you continuously meet your demands in the future. UNIQUE IFP™ AUTOMATED LOADER * MULTIPLY YOUR PRODUCTION CAPABILITY BY 4 The IFP™ Loader* enables you to carry out independent multiple runs of multiple molecules or of a single tracer. Four  consecutive...

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SYNTHERA® + BETTER, SMARTER, STRONGER.-6

STRONGER INCREASED UPTIME, REDUCED MAINTENANCE YOUR FULLY INTEGRATED RADIOPHARMACY All Synthera®+ electronic components are placed outside of the hot cell to ensure higher resistance to radiation damage, leading to longer hardware life time, reduced maintenance and increased uptime. INTEGRALAB® SOLUTION FROM PROJECT TO REALITY IBA IntegraLab® is a fully integrated solution combining equipment and services for the establishment of your (c)GMP radiopharmaceutical production centers. The synthesizer is the heart of your (c)GMP radiopharmaceutical process. The Integralab® team of experts will help...

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SYNTHERA® + BETTER, SMARTER, STRONGER.-7

TECHNICAL FEATURES SYNTHERA® CONSUMABLES IFP™ - Single-use system - Double wrapping pack - Plastic frame - Up to 6 vials, 2 cartridge holders - 1 reactor vial - Integrated interconnecting tubes Reagent Sets SYNTHERA®+ SYNTHESIZER SYNTHERA®+ HPLC Integrated software Up to several Synthera®+ units & accessories Synthera®+ HPLC Graphical interface Microsoft® Windows-based Remote access - ully automated synthesizer F with auto-ejectable system - adiation, temperature,gas R & compressed air sensors - eating system up to 180° H (c)GMP compliance - assword protected three-level access P software - rotected...

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SYNTHERA® + BETTER, SMARTER, STRONGER.-8

iba-synthera.com IBA Group | Synthera®+ | March 2021 © | All right reserved ABOUT IBA IIBA (Ion Beam Applications) is a global medical technology company focused on bringing integrated and innovative solutions for the diagnosis and treatment of cancer. The company’s expertise lies in the development of next-generation proton therapy technologies and radiopharmaceuticals that provide oncology care providers with premium quality services and equipment, including IBA’s leading fully-integrated IntegraLab® system. ABOUT IBA RADIOPHARMA SOLUTIONS Based on longstanding expertise, IBA RadioPharma Solutions...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.